An observational study on the effect of high versus low carbon dioxide pressure in laparoscopic cholecystectomy


  • Jenishkumar V. Modi Department of Surgery, Surat Municipal Institute of Medical Education And Research, Surat, Gujarat, India
  • Mitesh Trivedi Department of Surgery, Surat Municipal Institute of Medical Education And Research, Surat, Gujarat, India



Low CO2 pressure, High CO2 pressure, Laparoscopic cholecystectomy



Background: Gall bladder stone is one of the common diseases of hepatobiliary system. If it is symptomatic then it needs to be treated and sometimes it may lead to multiple complications. Laparoscopic approach for cholecystectomy is widely acceptable and routinely done procedure for gall bladder stone. Laparoscopic cholecystectomy reduces postoperative pain and hospital stay as compared to open surgery. Laparoscopic surgeries require carbon dioxide (CO2) to inflate peritoneal cavity.

Methods: It is an observational study at tertiary care centre. In present study authors have included all patients undergoing elective laparoscopic cholecystectomy. Patients required conversion to open cholecystectomy from laparoscopic cholecystectomy and emergency laparoscopic cholecystectomy and laparoscopic cholecystectomy for malignancy were not included. In present study, patients were randomly allocated into two groups: group A (n=50) low CO2 pressure (8-10 mmHg) pneumoperitonium and group B (n=50) high CO2 pressure (12-14 mmHg) pneumoperitonium to perform laparoscopic cholecystectomy. In present study authors have compared post operative effects in term of pain (at 4, 8 and 12 hrs post operatively), hospital stay and requirements of injectable analgesics between group A and group B.

Results: 14 patients in group B complained of post operative shoulder tip pain as compared to only 5 patients in group A. Analgesic requirement and mean length of post operative hospital stay were also less in group A as compared to group B.

Conclusions: Low pressure laparoscopic cholecystectomy (LPLC) significantly decrease the frequency and intensity of post operative shoulder tip pain. So, LPLC decrease the demand for postoperative analgesics and decrease post operative hospital stay.

Author Biographies

Jenishkumar V. Modi, Department of Surgery, Surat Municipal Institute of Medical Education And Research, Surat, Gujarat, India

General surgery

Mitesh Trivedi, Department of Surgery, Surat Municipal Institute of Medical Education And Research, Surat, Gujarat, India

General Surgery


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Original Research Articles