A case of mesenteric gastro intestinal stromal tumors: a diagnostic dilemma

Rajalakshmi R.; Rajakumar V.

doi:10.18203/2349-2902.isj20223176

Authors

Rajalakshmi R. Department of Surgery, Dr. Rangarajan Memorial Hospital, Chennai, Tamil Nadu, India
Rajakumar V. Department of Surgery, Dr. Rangarajan Memorial Hospital, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-2902.isj20223176

Keywords:

GIST, Mesenteric GIST, KIT mutation, Surgical resection, Imatinib

Abstract

Gastro intestinal stromal tumors (GIST) are non-epithelial tumors of gastrointestinal tract (GIT) arising from mesenchymal cells and interstitial cells of Cajal. It accounts for <1% of all of gastro-intestinal (GI) tumors and <5% of all GI malignancies. GIST most commonly involves stomach and small intestine, but rarely involves mesentery. Surgical resection is the main stay of treatment. Post-operative use of imatinib, delays the recurrence and improves the survival rate. In our study, we report a case of mesenteric GIST, a very rare entity and discuss the course of clinical presentation, diagnosis, management and prognosis.

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Author Biographies

Rajalakshmi R., Department of Surgery, Dr. Rangarajan Memorial Hospital, Chennai, Tamil Nadu, India

Postgraduate resident

Department of Surgery

Rajakumar V., Department of Surgery, Dr. Rangarajan Memorial Hospital, Chennai, Tamil Nadu, India

Consultant

Department of Surgery

References

Nilsson B, Bümming P, Meis‐Kindblom JM, Odén A, Dortok A, Gustavsson B et al. Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era: a population‐based study in western Sweden. Cancer. 2005;103(4):821-9.

Das AK, Begum T, Bedanta Barman PA. Mesenteric GIST: A case report. J Med Res. 2018;4(1):4-6.

Zhao X, Yue C. Gastrointestinal stromal tumor. J Gastrointestinal Oncol. 2012;3(3):189.

Feng F, Feng B, Liu S, Liu Z, Xu G, Guo M et al. Clinicopathological features and prognosis of mesenteric gastrointestinal stromal tumor: evaluation of a pooled case series. Oncotarget. 2017;8(28):46514.

Engin G, Asoglu O, Kapran Y, Mert G. A gastrointestinal stromal tumor with mesenteric and retroperitoneal invasion. World journal of surgical oncology. 2007;5(1):1-6.

Kirby R, Rajasagaram N, Ghusn M. Primary mesenteric gastrointestinal stromal tumour. J Surgical Case Rep. 2014;2014(5).

Sato M, Sato M, Yokoyama T, Kusaka A, Suzuki Y, Fukuhara K. A case of an intramesenteric GIST accurately diagnosed and completely resected by PET-CT and laparoscopy after gastrectomy for gastric cancer. J Surgical Case Rep. 2022;2022(6):rjac246.

Formanez AJ, Galvan-Bravo GN. Gastrointestinal Stromal Tumor of the Tongue. Philippine J Otolaryngol Head Neck Surg. 2013;28(1):28-33.