Bactibilia-effect on postoperative course and outcome in patients with bilio-pancreatic diseases

A. Dinakar Reddy; Anuroop Thota; Vanga Devi Harsha

doi:10.18203/2349-2902.isj20214829

Authors

A. Dinakar Reddy Department of Surgical Gastroenterology, NRI Medical College, Chinnakakani, Guntur, Andhra Pradesh, India
Anuroop Thota Department of General Surgery, NRI Medical College, Chinnakakani, Guntur, Andhra Pradesh, India
Vanga Devi Harsha Department of General Surgery, NRI Medical College, Chinnakakani, Guntur, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2349-2902.isj20214829

Keywords:

Bile, Bactibilia, Biliary stenting, Biliary microbial flora

Abstract

Background: Bactibilia is detrimental to the outcomes of biliary tract surgery. The present study was undertaken to determine the microbial flora of bile and their significance to post-operative infectious complications and morbidity.

Methods: A retrospective study of patients with biliopancreatic diseases who underwent surgery from Jan 2017 to March 2020 in a tertiary care hospital were analyzed. The samples were assessed for bile microbiological flora, and a search for their possible link with post-operative infectious complications and morbidity was carried out.

Results: A total of 90 bile samples were assessed. The mean age of the study group was 51.8 SD-13.6 years with male predominance. Bactibilia was found in 39 cases (43.3%), mostly in patients with malignant diseases, older than 50 years and females. Escherichia coli was the most common organism. Post-operative infectious complications were seen in twenty cases, thirteen of them in bactibilia-associated patients, showing statistical significance. Statistical significance was found between the presence of pre-operative biliary stent and bactibilia and between diabetes mellitus and bactibilia. Nine out of 24 patients with comorbidities had post-operative infectious complications. No significant relationship was found between pre-operative jaundice and comorbidities with bactibilia.

Conclusions: The present study showed a statistically significant relationship between the presence of pre-operative biliary stent and bactibilia and also the incidence of post-operative infectious complications and bactibilia. Microbiological analysis of bile is a valuable tool in prognosticating the post-operative complications, thereby guiding us to provide adequate therapy and helps to establish local antibiotic guidelines.

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