Quality of life assessment in patients of bladder cancer with radical cystectomy and ileal conduit
DOI:
https://doi.org/10.18203/2349-2902.isj20195115Keywords:
Bladder cancer, Radical cystectomy, Ileal conduit, Quality of life, QuestionnaireAbstract
Background: Bladder cancer, a lethal disease accounts for 3% of cancer deaths. With possibility of various urinary diversion options after bladder removal having comparable cancer control and complications, quality of life becomes an important factor in deciding the type of urinary diversion.
Methods: Retrospective observational study with statistically appropriate sample size of 50. Patients of radical cystectomy and ileal conduit given validated Functional Assessment Of Chronic Illness Therapy for Bladder Cancer ( FACT-Bl ) Questionnaire to answer about post-operative quality of life in terms of five parameters i.e., physical, mental, social, emotional and cancer specific well-being after 1 year of surgery.
Results: Results analysed by FACIT-Bl questionnaire analysis methods statistically, in terms of total scores and sub-scores. In our study the mean scores of physical well-being (PWB) subscale is 24.08±4.67 (range o-28), social well-being (SWB) subscale is 23.52±4.35 (range 0-28) , emotional well-being (EWB) subscale is 20.06±5.09, functional well-being (FWB) subscale is 21.84±6.01 (range 0-28), bladder cancer subscale is 36.44±5.72 (range 0-48). While mean trial outcome index score is 82.16±3.5 (range 0-104), FACT- General (G) score is 89.50+ 15.88 and mean FACT-Bl total score is 125.94±19.04.These scores provides the quantitative assessment of the quality of life and higher scores indicates better quality of life.
Conclusions: Assessing quality of life for a particular type of urinary diversion, with questionnaires, gives surgeons and patients, guidance regarding diversion of choice.
Metrics
References
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010, CA. Cancer J Clinicians. 2010;60(5):277–300.
Porter MP, Wei JT, Penson DF. Quality of life issues in bladder cancer patients following cystectomy and urinary diversion. Urologic Clinics North Am. 2005;32(2):207–16.
Bottleman MF, Pashos CL, Hauser RS, Laskin BL, Rednelli A. Quality of life aspects of bladder cancer. A review of literature. Quality of life Res. 2003;12:675-88.
Testa MA, Simonson DC. Assessment of quality-of-life outcomes. New England J Med. 1996;334(13):835–40.
Webster K, Cella D, Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) Measurement System: Properties, applications, and interpretation. Health and Quality of Life Outcomes. 2003;1:79.
Hart S, Skinner EC, Meyerowitz BE, Boyd S, Lieskovsky G, Skinner DG. Quality of life after radical cystectomy for bladder cancer in patients with an ileal conduit, cutaneous or urethral kock pouch. J Urol. 1999;162(1):77–81.
Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, et al. The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. J Clin Oncol. 1993;570-9.
Madersbacher S, Schmidt J, Eberle JM. Long term outcome of ileal conduit diversion. J Urol. 2003;169:985–90.
Mansson A, Colleen S, Hermeren G, Johnson G. Which patients will benefit from psychosocial intervention after cystectomy for bladder cancer? Br J Urol. 1997;80(1):50–7.
Rocco F, Scardino E, Carmignani L, Frea B, Strada G, Kocjancic E, et al. Orthotopic ileal neobladders in men and women: Techniques and comparison. Arch Ital Urol Androl. 1996;68(5):293–8.
Hardt J, Filipas D, Hohenfellner R, Egle UT. Quality of life in patients with bladder carcinoma after cystectomy: First results of a prospective study. Qual Life Res. 2000;9(1):1–12.
Fujisawa M, Isotani S, Gotoh A, Okada H, Arakawa S, Kamidono S. Health-related quality of life with orthotopic neobladder versus ileal conduit according to the SF-36 survey. Urology. 2000;55(6):862–5.
Weijerman PC, Schurmans JR, HopWC, Schroder FH, Bosch JL. Morbidity and quality of life in patients with orthotopic and heterotopic continent urinary diversion. Urology. 1998;51(1):51–6.
Vallorosi CJ, Wei JT, Gerlach M, Wood DP, Montie JE. Gender differences in urinary function after orthotopic neobladder. J Urol. 1999;161(4):90.
McGuire MS, Grimaldi G, Grotas J, Russo P. The type of urinary diversion after radical cystectomy significantly impacts on the patient’s quality of life [see comments]. Ann Surg Oncol. 2000;7(1):4–8.
Kitamura H, Miyao N, Yanase M, Masumori N, Matsukawa M, Takahashi A, et al. Quality of life in patients having an ileal conduit, continent reservoir or orthotopic neobladder after cystectomy for bladder carcinoma. Int J Urol 1999; 6(8): 393–399.
Kikuchi E, Horiguchi Y, Nakashima J, Ohigashi T, Oya M, Nakagava K, et al. Assessment of Long-Term Quality of Life Using the FACT-BL Questionnaire in Patients with an Ileal Conduit, Continent Reservoir, or Orthotopic Neobladder. Jpn J Clin Oncol. 2006;36(11):712-6.
Kristina HK, Karry SC, Scott N, Peter V. Association between exercise & quality of life in bladder cancer survivor: A population based study. Cancer Epidemiol Biomarkers Prev. 2007;16(5).