Angiomyolipoma of colon: unusual presentation


  • Vidhyachandra Gandhi Department of GI Surgery, Ruby Hall Clinic, Pune, Maharashtra, India
  • Swapnil Karnik Department of Pathology, Ruby Hall Clinic, Pune, Maharashtra, India
  • Nitin Pai Department of Gastroenterology, Ruby Hall Clinic, Pune, Maharashtra, India
  • Sujai Hegde Department of Surgical Oncology, Ruby Hall Clinic, Pune, Maharashtra, India



Angiomyolipomas, Intussusception, Colon


Angiomyolipomas are benign mesenchymal tumors mostly arising from the kidney. Angiomyolipoma of the colon is extremely rare. Here we report the findings of a 72 years gentleman who presented with recurrent episodes of abdominal pain and fullness of one year duration. Colonoscopy was suggestive of polypoidal lesion in the descending colon. CECT abdomen revealed a colocolic intussusception in the descending colon with lipoma as a leading point. He underwent a standard left hemicolectomy. Histopathological examination showed that the tumor of 5.7 cm in diameter included smooth muscle (spindle cell type), mature adipose tissue, and vessels, and therefore a diagnosis of angiomyolipoma was made. We believe this is the second report of colonic angiomyolipoma presenting with colocolic intussusception. 


Morgan GS, Straumfjord JV, Hall EJ. Angiomyolipoma of the kidney. J Urol. 1951;65(4):525-7.

Li T, Wang L, Yu HH, Sun HC, Qin LX, Ye QH, et al. Hepatic angiomyolipoma: a retrospective study of 25 cases. Surg Today. 2008;38(6):529–35.

Nelson CP, Sanda MG. Contemporary diagnosis and management of renal angiomyolipoma. J Urol 2002;168(4 Pt 1):1315–25.

Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA. Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors. Kidney Int. 2006;70(10):1777–82.

Hikasa Y, Narabayashi T, Yamamura M, Fukuda Y, Tanida N, Tamura K, et al. Angiomyolipoma of the colon: a new entity in colonic polypoid lesions. Gastroenterol Jpn. 1989;24(4):407–9.

Maesawa C, Tamura G, Sawada H, Kamioki S, Nakajima Y, Satodate R. Angiomyolipoma arising in the colon. Am J Gastroenterol. 1996;91(9):1852–4.

Maluf H, Dieckgraefe B. Angiomyolipoma of the large intestine: report of a case. Mod Pathol 1999;12(12):1132–6.

Chen JS, Kuo LJ, Lin PY, Changchien CR. Angiomyolipoma of the colon: report of a case and review of the literature. Dis Colon Rectum. 2003;46(4):547–9.

Sharara AI, Tawil A. Angiomyolipoma of the colon. Clin Gastroenterol Hepatol. 2005;3(9):35.

Cheng H, Sitrin MD, Rani A. Angiomyolipoma in the colon. Gastrointest Endosc 2006;64(3):443–4.

Oishi K, Fukuda S, Sakimoto H, Eto T, Takahashi M, Nishida T. Angiomyolipoma of the colon: report of a case. Surg Today. 2009;39(11):998-1001.

Pukar M. Angiomyxolipoma of transverse colon – a case report. Turk J Gastroenterol. 2012;23(2):156-9

Yamakado K, Tanaka N, Nakagawa T, Kobayashi S, Yanagawa M, Takeda K. Renal angiomyolipoma: relationships between tumor size, aneurysm formation, and rupture. Radiology. 2002;225(1):78–82.

Kim JK, Park SY, Shon JH, Cho KS. Angiomyolipoma with minimal fat: differentiation from renal cell carcinoma at biphasic helical CT. Radiology. 2004;230 (3):677–84.

Jinzaki M, Tanimoto A, Narimatsu Y, Ohkuma K, Kurata T, Shinmoto H, et al. Angiomyolipoma: imaging findings in lesions with minimal fat. Radiology. 1997;205(2):497–502.

Acikalin MF, Tel N, Oner U, Pasaoglu O, Donmez T. Epithelioid angiomyolipoma of the kidney. Int J Urol. 2005;12(2):204–7.

Kawaguchi K, Oda Y, Nakanishi K, Saito T, Tamiya S, Nakahara K, et al. Malignant transformation of renal angiomyolipoma: a case report. Am J Surg Pathol. 2002;26(4):523–9






Case Reports