Thrombophlebitis at infusion sites in surgical ward: a clinical study


  • Rajeev Dwivedi Department of Anaesthesiology, S. S. Medical College, Rewa, Madhya Pradesh, India
  • Atul Kumar Singh Department of Surgery, S. S. Medical College, Rewa, Madhya Pradesh, India
  • A. P. S. Gaharwar Department of Surgery, S. S. Medical College, Rewa, Madhya Pradesh, India



Basilic vein, Critically ill, Intravenous cannualation, Surgical ward, Saphenous vein, Thrombophlebitis incidence


Background: Peripheral venous Cannulation is indispensable in admitted patients in surgical ward, thrombophlebitis following infusion is seldom serious, but it effects on postoperative recovery, hospital stay and hence burden of disease are magnanimous. The objective of the study to know the common sites of thrombophlebitis, Frequency of thrombophlebitis in relations to type of fluid and drugs used, and to find out the incidence of thrombophlebitis in relation to diseased condition and type of surgical patient.

Methods: this prospective observational study was conducted on 300 patients admitted in surgical ward of S.S Medical College and associated S.G.M. hospital, Rewa (M.P.) patients selected randomly. These Patients were visited daily for any sign and symptoms at infusion site. The incidence of thrombophlebitis according to common infusion sites, in relations to type of fluid and drugs used and in relation to diseased condition and type of surgical patients were recorded. The tool designed to collect the data were sociodemographic Performa and observational check list.

Results: In total 300 patients the incidence of thrombophlebits is highest (100%) in Saphenous vein (Lower Limb) minimum (17%) in Basilicvein (Upper Limb). Incidence of thrombophlebitis is higher in earlier days (within 2 days) of infusion with Dextrose containing fluid (D5%+ D10%) and higher in critically ill and emergency operated patients.

Conclusions: Thrombophelebitis is still an important ongoing problem in admitted patients in surgical ward. Incidence is highest in saphenous vein, with dextrose containing fluid and in critically ill & emergency operated patients.  It has definite relationship with site of infusion site, type of fluid, illness of patients and nature of operation


Sharifi J, Ghavami F, Nowrouzi Z, Fouladvand B, Malek M, Rezaeian M., et al. Oral versus intravenous rehydration therapy in severe gastroenteritis . Arch Dis Child.1985;60:856-60.

Oliveria AS, Parreira PM. Nursing intervention and peripheral venous catheter related phlebitis. Systemic literature review.Referencia: Scientific Journal of the health Science Research Unit: Nursing. 2010;3:137-47.

Jackson A. Infection control: a battle in infusion phlebitis. Nursing Times.1998;94:4:68-71.

Bhandari B, Joshi T, Tak SK, Anti –cogulant in the prevention of post- infusion thrombophlebitis in children. Indian Paeditr.1979:46:289-94

Infusion Nurses Society Standards of Practice. Vascular access device selection and placement. JInfus Nurs. 2012;S37

Lanbeck P, Odenholt, I, Paulsen O. Dicloxicillin: A higher risk than cloaxacillin for infusion phlebitis. Scand J Infect Dis. 2003;35:397-400.

Maki D and Ringer M. Risk factors for infusion –related phlebitis with small peripheral venous catheter. Annals of Internal Med, 1991;114:845-54.

Cicolini G, Bonghi AP, Di Labio L, Di Mascio R. Position of peripheral venocannulae and the incidence of thrombophlebitis: an observation study. J Adv Nurse. 2009:65:1268-73

Royal College of Nursing(RCN).2010. Standards of infusion therapy.

Tagalakis, V., Kahn,S., Libman, M and Biostein, M. .The epidemiology of peripheral vein infusion thrombophlebitis: a critical review. Amer J Med, 2002;113:146-51.

Uslusoy E, Mete S, Predisposing factors to phlebitis intravenous catheters: a descriptive study. J Am Ac: Nurse Pract. 2008:20;172-80.

Reguerio Pose M.Pheripheral venous catheters–incidence of thrombophlebitis and its determining factors. Revista de Enfermeria. 2005;28;21-8.

Carballo, M., Linas M. and Feijoo, M. {Phlebitis in pheripheral catheters(I). Incidence and risk factors}. Revista de Enferneria, 2004;27:34-8.

Ferreira L R, Pedreira M L and Diccini S. Phlebitis among neurosurgical patients. ActaPaulista de Enfermagnem. 2007;20:30-6.

Mermel LA and Maki DG. Infectious complications of swan- Ganz pulmonary artery catheters, Pathogenesis, epidiomology, prevention and management. Am J Respir Crit Care Med. 1994; 149:1020-3.

Monreal M, Quilez F, Rey-Joly C, Rodriguez S, Sopena N, Neira C, et al. Infusion phlebitis in patient with acute pneumonia. A Prospective study.Chest. 1999;115:1576-80.






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