Parathyroid adenoma in a 33 years female, manifesting as non-traumatic multiple bone fractures

Authors

  • Mihir Sardhara Department of General Surgery, New Civil Hospital, Surat, Gujarat, India
  • Nikhil Reddy Department of General Surgery, New Civil Hospital, Surat, Gujarat, India

DOI:

https://doi.org/10.18203/2349-2902.isj20233349

Keywords:

Parathyroid adenoma, Hyperparathyroidism, Hypercalcemia, Non-traumatic fractures, Fatigue

Abstract

A 33 years old female patient presented to OPD with chief complaints of prolonged fatigue, abnormal gait and difficulty in walking since 7 years. On further evaluation MRI pelvis revealed bilateral non-traumatic pelvic bone fractures, with high Serum parathyroid hormone level (1050 pcg/ml) and hypercalcemia. CECT Neck showed a well-defined soft tissue density lesion involving the posterior-inferior aspect of the right lobe of thyroid gland. Surgical resection was performed and histopathology revealed parathyroid adenoma. Clinical manifestations and PTH and calcium levels gradually decreased to normal after surgery. Patient’s symptoms gradually decreased over a period of 2 month after treatment of the underlying cause. In a young female presenting with bony pains and non-traumatic fractures, a differential diagnosis of parathyroid adenoma must be kept in mind.

 

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References

Prihantono P, Palinggi E, Haryasena H, Hamdani W, Binekada IMC. Surgical Treatment for Parathyroid Adenoma: A Case Report. Open Access Maced J Med Sci. 2019;7(15):2497-2501.

Kantharia SR, Kantharia RA, Reddy PK, Mistry YM. Parathyroid adenoma: a case report. Int J Otorhinolaryngol Head Neck Surg. 2020;6:1533-7.

Johnson NA, Tublin ME, Ogilvie JB. Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR Am J Roentgenol. 2007;188(6):1706-15.

Khan AA, Khatun Y, Walker A, Jimeno J, Hubbard JG. Role of intraoperative PTH monitoring and surgical approach in primary hyperparathyroidism. Ann Med Surg (Lond). 2015;4(3):301-5.

Erickson LA. Atlas of Endocrine Pathology: Atlas of Anatomic Pathology. Springer. 2014:121130.

Clark PB, Perrier ND, Morton KA. Detection of an intrathymic parathyroid adenoma using single-photon emission CT 99mTc sestamibi scintigraphy and CT. AJR Am J Roentgenol. 2005;184(3):S16-8.

Smith JR, Oates ME. Radionuclide imaging of the parathyroid glands: patterns, pearls, and pitfalls. Radiographics. 2004;24(4):1101-15.

Kantharia SR, Kantharia RA, Reddy PK, Mistry YM. Parathyroid adenoma: a case report. Int J Otorhinolaryngol Head Neck Surg 2020;6:1533-7.

Lorberboym M, Minski I, Macadziob S, Nikolov G, Schachter P. Incremental diagnostic value of preoperative 99mTc-MIBI SPECT in patients with a parathyroid adenoma. J Nucl Med. 2003;44(6):904-8.

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Published

2023-10-27

How to Cite

Sardhara, M., & Reddy , N. (2023). Parathyroid adenoma in a 33 years female, manifesting as non-traumatic multiple bone fractures. International Surgery Journal, 10(11), 1828–1830. https://doi.org/10.18203/2349-2902.isj20233349

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Section

Case Reports