Angiomyxoma of thigh in a young lady: rare presentation
DOI:
https://doi.org/10.18203/2349-2902.isj20232999Keywords:
Myxoid myxoma, Angiomyxoma, Extracellular matrix, Neoplasms, SarcomaAbstract
Angiomyxoma is a rare tumor that typically occurs in the perineum in women of reproductive age. It is very rare to present in the subcutaneous plane at thigh region in a young female. Angiomyxoma belongs to one group of myxomas tumors. They occur at various locations such as heart, bones, skin subcutaneous and aponeurotic tissues, urogenital tract and skeletal muscles. These tumors are characterized by having abundant mucoid and myxoid extracellular matrix. Angio myxoma is a rare benign mesenchymal tumor in approximately in 95% cases. The incidence is reported as varying from 0.1 to 0.13 per 100,000 population. These tumors are encompassing a broad spectrum of clinical behavior ranging from benign to malignant. Most of these tumors located in intramuscular plane and in our case the tumor located in the subcutaneous plane and presented in a young lady. We have done wide local excision for that tumor and came out as cutaneous angiomyxoma of thigh. We are concluding that due to these tumors having broad spectrum of clinical behavior as well as high rate of recurrence, preoperatively thoroughly investigated to rule out the soft tissue sarcomatous conditions as well as to plan exact mode of treatment.
Metrics
References
Yaligod VMAS. Intramuscular myxoma-a rare tumor. J Orthop Case Rep. 2013;3(4):38.
Baheti AD, Tirumani SH, Rosenthal MH, Howard SA, Shinagare AB, Ramaiya NH et al. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015;204(2):374-85.
Outwater EK, Marchetto BE, Wagner BJ, Siegelman ES. Aggressive angiomyxoma: findings on CT and MR imaging. AJR 1999;172:435-8.
Fetsch JF, Laskin WB, Lefkowitz M, et al. Aggressive angiomyxoma: a clinicopathological study of 29 female patients. Cancer. 1996;78:79-90.
Heffernan EJ, Hayes MM, Alkubaidan FO, Clarkson PW, Munk PL. Aggressive angiomyxoma of the thigh: case report. Skeletal Radiol. 2008;37(7):673-8.
Steeper TA and Rosai J. Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynaecologic soft-tissue neoplasm. Am J Surg Pathol. 1983;7:463-75.
Nakamura T, Miura K, Maruo Y, Sunayama K, Maruyama K, Kashiwabara H et al. Aggressive angiomyxoma of the perineum originating from the rectal wall. J Gastroenterol. 2002;37(4):303-8.
Kim HM, Pyo JE, Cho NH, Kim NK, Kim MJ. MR imaging of aggressive angiomyxoma of the female pelvis: case report. JKSMRM. 2008;12:206-10.
Murphey MD, McRae GA, Fanburg-Smith JC, Temple HT, Levine AM, Aboulafia AJ. Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 2002;225(1):215-24.
Srinivasan S, Krishnan V, Ali SZ, Chidambaranathan N. “Swirl sign” of aggressive angiomyxoma-A lesser known diagnostic sign. Clin Imaging. 2014;38:751.
Sutton BJ, Laudadio J. Aggressive angiomyxoma. Arch Pathol Lab Med. 2012;136(2):217-21.
Amezcua CA, Begley SJ, Mata N, Felix JC, Ballard CA. Aggressive angiomyxoma of the female genital tract: a clinicopathologic and immunohistochemical study of 12 cases. Int J Gynecol Cancer. 2005;15(1):140-45.
McCluggage W, Patterson A, Maxwell P. Aggressive angiomyxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol. 2000;53:603-5.
Jingping Z, Chunfu Z. Clinical experiences on aggressive angiomyxoma in China (report of 93 cases). Int J Gynecol Cancer. 2010;20:303-7.
Wiser A, Korach J, Gotlieb W, Fridman E, Apter S, Ben-Baruch G. Importance of accurate preoperative diagnosis in the management of aggressive angiomyxoma: report of three cases and review of the literature. Abdom Imaging. 2006;31:383-6.
Özbek N, Danaci M, Okumuş B. Recurrent intramuscular myxoma: review of the literature, diagnosis and treatment options. Turk J Can. 2006;36:75-8.
