The role of methylene blue in mitigating surgical morbidity in parotid surgery: a comprehensive review


  • Soumith Subhash Department of Surgery, Bokaro General Hospital, Bokaro, Jharkhand, India
  • Udit Bagchi Department of Surgery, SCB Medical College and Hospital, Cuttack, Odisha, India
  • Suraj Ethiraj Department of Surgery, SCB Medical College and Hospital, Cuttack, Odisha, India



Parotidectomy, MB, Postoperative complication, Facial nerve, Freys syndrome


Parotid surgery is associated with specific surgical morbidity, including temporary facial weakness, permanent facial nerve injury, post-parotidectomy depression, and Frey's syndrome (gustatory sweating). Despite various modifications implemented to reduce surgical morbidity, complications, particularly facial nerve injury, remain a challenge. To overcome this difficulty, the use of an identification method, such as preoperative intravital staining of the gland with methylene blue (MB), has been proposed. This article provides a comprehensive review of the role of MB in parotid surgery, discussing its potential benefits, safety profile, and future directions for research.



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