Central giant cell granuloma in a 10-year-old girl: microsurgical reconstruction with a microvascularized fibula flap

Authors

  • Ricardo Alberto Pulido-López Department of General Surgery, Universidad Nacional Autónoma de México; Hospital Central Sur de Alta Especialidad, Petróleos Mexicanos, Ciudad de México
  • Humberto Gustavo Martínez-Martínez Department of General Surgery, Universidad de Monterrey; Unidad Médica de Alta Especialidad No. 25, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León
  • Héctor Manuel Suárez-Ortega Department of Plastic Surgery, Universidad Autónoma del Estado de México; Centro Médico Lic. Adolfo López Mateos, Instituto de Salud del Estado de México, Toluca, Estado de México
  • Gabriel Yamil Tego-Ortiz Department of Plastic Surgery, Universidad Nacional Autónoma de México; Hospital General Dr. Rubén Leñero, Secretaria de Salud de la Ciudad de México, Ciudad de México

DOI:

https://doi.org/10.18203/2349-2902.isj20231975

Keywords:

CGCG, Central giant cell lesion, Mandibular diseases, Surgical approach

Abstract

Central giant cell granuloma (CGCG) are rare, proliferative, benign bone tumors characterized by an abundance of multinucleated giant cells. It affects children and young adults, predominantly women, in the second and third decade of life, it’s commonly found in the mandible. The main treatment for giant cell tumors is surgical excision with free histologic margins; in case of mandibular involvement, the use of a vascularized composite bone flap represents the standard for a functional reconstruction. We present the case of a female patient in the first decade of life with a CGCG of aggressive type, located in the ascending branch and right mandibular angle. En bloc resection of the lesion was performed, with a 2-cm margin and mandibular reconstruction at the same surgical time with a free microvascularized flap from the right fibula. CGCG are rare and infrequent tumors during childhood. Due to its uncertain behavior, it is important to rule out other differential diagnoses prior to definitive treatment.

References

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Published

2023-06-28

Issue

Section

Case Reports