Breast cancer, Clinical presentations, Risk factors, Staging

Authors

  • Mohammad Fazelul Rahman Shoeb Department of General Surgery, GIMS, Gulbarga, Karnataka, India
  • Anil Reddy Pinate Department of General Surgery, GIMS, Gulbarga, Karnataka, India
  • Poonam Prakash Shingade Department of Community Medicine, ESIC, MC, Gulbarga, Karnataka, India

DOI:

https://doi.org/10.18203/2349-2902.isj20170207

Keywords:

Breast cancer, Clinical presentations, Risk factors, Staging

Abstract

Background: Breast cancer is most common cause of cancer related mortality and second most common cause of cancer in females in India. Hence study aims to evaluate the clinical profile and risk factors of the breast cancer.

Methods: This is cross sectional study done at Victoria hospital and Bowring and Lady Curzon Hospital between January 2012 to October 2012 among 50 females patients more than 18 years of age, presented with breast cancer irrespective of tumour stage, size and location and for whom preliminary diagnosis of carcinoma breast was confirmed on fine needle aspiration cytology. Preformed, pretested semi-structured questionnaire was used to collect the data regarding the risk factors and clinical presentations of the patients.

Results: Maximum participants 18 (36%) were in the age group of 41-50 years, 32 (64%) patients belonged to lower class with mean age at menarche of 13.3 years. About 26 (52%) patients were in premenopausal state. In present study, 48 (96%) of the total patients were multiparous and 47 (94%) women practiced breast feeding for more than 4 months. None of the patients in this study had a family history of breast cancer. Most breast cancer patients presented with history of lump followed by pain 14 (28%) and nipple retraction 9(18%). Most of the patients 29(58%) had upper outer quadrant involvement followed by upper inner quadrant in 7 (14%).In about 26 (52%)patients, tumour size was more than 5 cm and 32 (64 %) patients had axillary lymph nodes.

Conclusions: Breast cancer was predominantly a disease of middle aged, lump in breast is commonest mode of presentation with upper outer quadrant involvement and 26 (52%) patients were in stage II of TNM classification.

Metrics

Metrics Loading ...

References

Michae IJ, Jemal A. Cancer epidemiology, prevention and screening. Hollan F. Cancer medicine. American Cancer Society. Philadelphia: BC Decker Inc; 2003:367-81.

Zeleniuch JA, Roy ES. Epidemiology of breast cancer. In: Roses FD, editors. Breast Cancer. 2nd edition. Philadelphia: Elsevier; 2005:3-14.

Yeole BB. Trends in cancer incidence in female breast, cervix uteri, corpus uteri, and ovary in India. Asian Pac J Cancer Prev. 2008;9:119-22.

Moore MA, Attasara P, Khuhaprema T, Le TN, Nguyen TH, Raingsey PP, et al. Cancer epidemiology in mainland South-East Asia - past, present and future. Asian Pac J Cancer Prev. 2010;2:67-80.

Kapur BM, Dhawan IK, Gupta RK, Sinha SN. Clinico pathological study of carcinoma breast. Indian J Cancer. 1974;11(1):28-32.

Sen A, Gupta TK. Cancer of breast and its treatment. Ind J Surg. 2009;11:832-47.

Eerola H, Aittomaki K, Seljavaara S, Nevanlinna H, Smitten K. Hereditary breast cancer and handling of patients at risk. Scand J Surg. 2002;91:280-7.

Bhattacharya S, Adhikary S. Evaluation of risk factors, diagnosis and treatment in carcinoma breast - a retrospective study. Kathmandu University Medical Journal. 2006;4(1):54-60.

Hunter DJ, Spiegelman D, Adami HO, Brandt PA, Folsom AR, Goldbohm RA, et al. Non-dietary factors as risk factors for breast cancer, and as effect modifiers of the association of fat intake and risk of breast cancer. Cancer Causes Control. 1997;8:49-56.

Lisa A, Newman. The Breast In F. Charles Brunicardi, Schwatz Principles of Surgery, 9th Edition, Mc Graw Hill. 2010:423-74.

Bloom BS, Pouvourville S, Chatre. Breast cancer treatment in clinical practice compared to evidence and practical guidelines. Brit J Canc. 2004;90:26-30.

Schaepveld M, Elisabeth GE, Winette TA. The prognostic effect of the number of histologically examined axillary lymph nodes in breast cancer: stage migration or age association. Annals Surg Oncology. 2006;13:465-74 .

Lin PP, Allison DC, Wainstock J. Impact of axillary lymph node dissection on the therapy of breast cancer patients. J Clinical Oncology. 2010;11:1536-44.

Downloads

Published

2017-01-25

How to Cite

Shoeb, M. F. R., Pinate, A. R., & Shingade, P. P. (2017). Breast cancer, Clinical presentations, Risk factors, Staging. International Surgery Journal, 4(2), 645–649. https://doi.org/10.18203/2349-2902.isj20170207

Issue

Section

Original Research Articles