Unusual cause of cervical lymphadenopathy in post-partum patient with atypical presentation: Kikuchi disease

Authors

  • Siti F. Abdul Razak Department of Otorhinolaryngology, Queen Elizabeth Hospital, Karung Berkunci, Kota Kinabalu, Sabah, Malaysia
  • Fong J. K. Department of Pathology, Queen Elizabeth Hospital, Karung Berkunci, Kota Kinabalu, Sabah, Malaysia
  • M. R. M. Yunus Department of Otorhinolaryngology Head and Neck Surgery, UKM Medical Centre, Kuala Lumpur, Malaysia
  • Elsie J. Anastasius Department of Otorhinolaryngology, Queen Elizabeth Hospital, Karung Berkunci, Kota Kinabalu, Sabah, Malaysia

DOI:

https://doi.org/10.18203/2349-2902.isj20231738

Keywords:

Lymphadenopathy, Kikuchi disease, Necrotising lymphadenitis

Abstract

Kikuchi-Fujimoto disease, also known as histiocytic necrotising lymphadenitis, is an unusual type of painful lymphadenopathy. It is a self-limiting benign disease; usual management includes supportive therapy. We described a case of Kikuchi Disease in a childbearing-age woman who presented with painless and localised cervical lymphadenopathy during her postpartum period. Histopathology of the affected cervical node reveals areas of apoptosis and necrosis with abundant foamy histiocytes and plasmacytoid monocytes. The cervical node resolves spontaneously, and no subsequent new cervical lymph node was observed in this patient. Patient was given reassurance. It is vital to recognise Kikuchi disease as one of the causes of persistent cervical lymphadenopathy, to provide optimal management and to avoid incorrect treatment.  

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References

Chiu CF, Chow KC, Lin TY, Tsai MH, Shih CM, Chen LM. Virus infection in patients with histiocytic necrotizing lymphadenitis in Taiwan. Detection of Epstein-Barr virus, type I human T-cell lymphotropic virus, and parvovirus B19. Am J Clin Pathol. 2000;113(6):774-81.

Kikuchi M, Yoshizumi T, Nakamura H. Necrotizing lymphadenitis: possible acute toxoplasmic infection. Virchows Arch A Pathol Anat Histol. 1977;376(3):247-53.

Allaf AW, Yahia YM. Kikuchi-Fujimoto Disease Associated with Sjögren's Syndrome: A Case Report. Eur J Case Rep Intern Med. 2018;5(5):000856.

Deaver D, Horna P, Cualing H, Sokol L. Pathogenesis, diagnosis, and management of Kikuchi-Fujimoto disease. Cancer Control. 2014;21(4):313-21.

Dumas G, Prendki V, Haroche J, Amoura Z, Cacoub P, Galicier L, et al. Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature. Medicine (Baltimore). 2014;93(24):372-82.

Singh JM, Shermetaro CB. Kikuchi-Fujimoto Disease in Michigan: A Rare Case Report and Review of the Literature. Clin Med Insights Ear Nose Throat. 2019;12:1179550619828680.

Das DK, Mallik MK, Dashti HA, Sathar SA, Jaragh M, Junaid TA. Kikuchi-Fujimoto disease in fine-needle aspiration smears: a clinico-cytologic study of 76 cases of KFD and 684 cases of reactive hyperplasia of the lymph node. Diagn Cytopathol. 2013;41(4):288-95.

Kuo TT. Kikuchi's disease (histiocytic necrotizing lymphadenitis). A clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology, and DNA ploidy. Am J Surg Pathol. 1995;19(7):798-809.

Veer V, Lim A, Issing W. Kikuchi-fujimoto disease: a case report and literature review. Case Rep Otolaryngol. 2012;2012:497604.

Ramirez AL, Johnson J, Murr AH. Kikuchi-Fujimoto's disease: an easily misdiagnosed clinical entity. Otolaryngol Head Neck Surg. 2001;125(6):651-3.

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Published

2023-05-30

How to Cite

Razak, S. F. A., J. K., F., Yunus, M. R. M., & Anastasius, E. J. (2023). Unusual cause of cervical lymphadenopathy in post-partum patient with atypical presentation: Kikuchi disease . International Surgery Journal, 10(6), 1071–1074. https://doi.org/10.18203/2349-2902.isj20231738

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Section

Case Reports