Non-steroidal anti-inflammatory drug-induced perforation of Meckel’s diverticulum

Authors

  • Manish Kumar Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Rahul Khanna Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Ram N. Meena Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Shashi P. Mishra Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Panchanana Panigrahy Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Akshay Anand Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
  • Binod Kumar Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2349-2902.isj20231758

Keywords:

Acute abdomen, Meckel’s diverticulum, Perforation peritonitis

Abstract

Meckel’s diverticulum (MD) is commonest congenital gastrointestinal anomaly, the common complications associated with MD are hemorrhage, ulceration, intestinal obstruction, diverticulitis, umbilical anomalies, and neoplasm. Perforation of Meckel’s diverticulum is a rare entity and there’s very less documentation regarding the incidence of Meckel’s perforation. MD perforation is usually a life-threatening complication and is associated with high mortality, perforation is usually due to diverticulitis, peptic ulcer disease occurring in the ectopic gastric mucosa which might be present in MD. NSAID intake associated with Merkel’s perforation has been documented in a few studies. NSAID intake and gastric perforation have been well established but a relation between NSAIDs and heterotrophic gastric mucosa of MD has not been documented. With NSAIDs use becoming very common it is, therefore, important to document this association.

 

References

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Espitia FT, Davila DM, Ramirez LV, Trujillo BS, Moyron LS, Salgado AM. Perforation of a Meckel’s diverticulum secondary to chronic NSAID use: case report and review of the literature. Int Surg J. 2020;7(9):3082.

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Published

2023-05-30

Issue

Section

Case Reports