Dermatofibrosarcoma protuberans - an atypical tumor with a typical diagnostic dilemma: a case report




Dermatofibrosarcoma protuberans, Recurrence, Misdiagnosis, Wide local excision


Dermatofibrosarcoma protuberans (DFSP) is a rare tumor of dermal fibroblast. Diagnosis poses a challenge to every surgeon. Its propensity to recur can be attributed to its characteristic finger-like projections, misdiagnosis, and incomplete excision. Wide local excision with adequate margins may lead to functional defects and cosmetic blemishes. Most cases undergoing second surgery warrants reconstructive procedure which might further complicate the management. We report a case of DFSP, initially misdiagnosed and underwent incomplete excision, later presented with recurrence and atypical features. High-grade suspicion is of paramount importance for ascertaining the diagnosis of DFSP and its appropriate treatment.


Manini I, Montomoli E. Epidemiology and prevention of human papillomavirus. Ann Ig. 2018;30(1):28-32.

Moscicki AB, Schiffman M, Kjaer S, Villa LL. Chapter 5: Updating the natural history of HPV and anogenital cancer. Vaccine. 2006;24(3):42-51.

Reis HL, Ferreira DC, Forattini AG, Souza PG, Curvelo JA, Passos MR. Genital and oral human papillomavirus infection in a patient from the group of women who have sex with women. Clinics (Sao Paulo, Brazil). 2010;65:1383-5.

Chikandiwa A, Kelly H, Sawadogo B, Ngou J, Pisa PT, Gibson L, et al. Prevalence, incidence and correlates of low risk HPV infection and anogenital warts in a cohort of women living with HIV in Burkina Faso and South Africa. PLoS One. 2018;13:e0196018.

Doorbar J, Egawa N, Griffin H, Kranjec C, Murakami I. Human papillomavirus molecular biology and disease association. Rev Med Virol. 2015;25(1):2-3.

Yakely AE, Avni-Singer L, Oliveira CR, Niccolai LM. Human papillomavirus vaccination and anogenital warts: a systematic review of impact and effectiveness in the United States. Sex Transm Dis. 2019;46:213-20.

Hamano I, Hatakeyama S, Yamamoto H, Fujita T, Murakami R, Shimada M, et al. Condyloma acuminata of the urethra in a male renal transplant recipient: a case report. Transplant Proc. 2018;50:2553-7.

Saeki Y, Sato S, Okajima K. Condyloma acuminatum of the nipple and areola. Int J Dermatol. 2014;53:e171-2.

Percinoto AC, Danelon M, Crivelini MM, Cunha RF, Percinoto C. Condyloma acuminata in the tongue and palate of a sexually abused child: a case report. BMC Res Notes. 2014;7:467.

Verma S. Bilateral linear location of condylomata acuminata in the groin: an uncommon presentation aggravated by topical steroids. Indian J Dermatol. 2014;59:636.






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