A novel approach for weight reduction after Roux-en-Y gastric bypass
Keywords:Diabesity, Type II diabetes mellitus, Obesity, Syndrome X, Gastric bypass, Bariatric surgery
Diabesity constitutes coexistence of both diabetes and obesity has become a modern epidemic now. It can be linked with insulin resistance and hyperinsulinaemia by various pathophysiological mechanism. Bariatric and metabolic surgery is a safe and effective treatment option for those affected by severe obesity and with its comorbidities like hypertension, diabetes mellitus, sleep apnoea, knee problems etc. These same procedures have also been recognized for their impact on metabolic or hormonal changes that play a major role in hunger (the desire to start eating) and satiety (the desire to stop eating) as well as improvement and/or resolution of conditions like diabetes mellitus, hyperlipidaemia which is associated with severe obesity. Bariatric surgery is a recognized and accepted approach for both weight-loss and many of the conditions that occur as a result of severe obesity.
Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37:1595-607.
Gloy VL, Briel M, Bhatt DL, Kashyap SR, Schauer PR, Mingrone G et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;347:f5934.
Alizadeh RF, Li S, Gambhir S, Hinojosa MW, Smith BR, Stamos MJ et al. Laparo-scopic sleeve gastrectomy or laparoscopic gastric bypass for patients with metabolic syndrome: an MBSAQIP analysis. Am Surg. 2019;85:1108-12.
Scopinaro N, Gianetta E, Adami GF. Biliopancreatic diversion for obesity at eighteen years. Surgery. 1996;119(3):261-8.
Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA. 2003;289;187-93.
Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724-37.
Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Brethauer SA, Navaneethan SD et al. Kashyap Bariatric surgery versus intensive medical therapy for diabetes–3-year outcomes N Engl J Med. 2014;370:2002-13.