Silent and silenced disease: a rare presentation of Chagas disease
DOI:
https://doi.org/10.18203/2349-2902.isj20223608Keywords:
Enteric nervous system, Gastrointestinal tract, Motility disorders, Chagas disease, Trypanosoma cruzi, Cardiac damageAbstract
Chagas disease is an infectious disease caused by the protozoan Trypanosoma cruzi. The disease mainly affects the nervous system, digestive system and heart. The objective of this article is to know about the chronic gastrointestinal manifestations of Chagas which are mainly a result of enteric nervous system impairment caused by T. cruzi infection. The anatomical locations most commonly described to be affected by Chagas disease are salivary glands, esophagus, lower esophageal sphincter, stomach, small intestine, colon, gallbladder and biliary tree. Most people suffer cardiac damage, including cardiomyopathy, heart rhythm abnormalities and often an apical aneurysm.
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References
Sastry AS, Bhat S. Essentials of Medical Parasitology Book. Jaypee Brothers Medical Publishers; Second edition (1 January 2018). 2018.
Koberle F. Chagas’ disease and Chagas’ syndromes: The pathology of American trypanosomiasis. Adv Parasitol. 1968;6:63-116.
Gurvits GE, Lan G. Enterolithiasis. World J Gastroenterol 2014;20(47):17819-29.
Joshi PP. Human trypanosomiasis in India: is it an emerging new zoonosis? In: Munjal YP, Editor, API Textbook of Medicine. 9th edition. New Delhi: Jaypee Brothers; 2013: 10-13.
Shrivastava KK, Shrivastava GP. Two cases of Trypanosoma (Herpetosoma) species infection of man in India. Trans R Soc Trop Med Hyg. 1974;68:3-4.
Verma A, Manchanda S, Kumar N, Sharma A, Goel M, Banerjee PS, et al. Trypanosoma lewisi or T. lewisi-like infection in a 37-day-old Indian infant. Am J Trop Med Hyg. 2011;85:221-4.
