Clinical study of various forms of acute pancreatitis in a tertiary care centre

Kautilya Patel; Sachin Jivani; Jahnavi Zala; Shashank Shukla; Rohan Gupta; Mukesh Pancholi

doi:10.18203/2349-2902.isj20222935

Authors

Kautilya Patel Department of Surgery, New Civil Hospital, Surat, Gujarat, India
Sachin Jivani Department of Surgery, New Civil Hospital, Surat, Gujarat, India
Jahnavi Zala Department of Surgery, New Civil Hospital, Surat, Gujarat, India
Shashank Shukla Department of Surgery, New Civil Hospital, Surat, Gujarat, India
Rohan Gupta Department of Surgery, New Civil Hospital, Surat, Gujarat, India
Mukesh Pancholi Department of Surgery, New Civil Hospital, Surat, Gujarat, India

DOI:

https://doi.org/10.18203/2349-2902.isj20222935

Keywords:

Acute pancreatitis, Necrosis, Pseudo cyst, Severe acute pancreatitis

Abstract

Background: Acute pancreatitis is an acute inflammatory process of the pancreas with variable involvement of regional tissues and remote organ system. Severe acute pancreatitis (SAP) is characterized by a short course of progressive multi organ dysfunction syndrome (MODS), early hypoxemia and increased incidence of necrosis, infection, and abdominal compartment syndrome (ACS). The average mortality rate in severe acute pancreatitis approaches 2-10%. This study was conducted to observe etiological factors, the clinical presentations and outcome of various form of acute pancreatitis.

Methods: A hospital record based retrospective study on one hundred (100) cases of various forms of acute pancreatitis in the department of surgery at tertiary care teaching hospital of South Gujarat from January 2019 to December 2019 to know the clinical presentation of acute pancreatitis patients.

Results: The maximum patients were belonged to age group between 31-40 years. There was a high incidence of alcoholic pancreatitis as compared to the gallstone pancreatitis. In both males and females, alcohol was the main etiological factor. Few patients needed ICU admission and oxygenation. Surgery was the modality for some patients. Out of total, 89 cases were recovered.

Conclusions: Early identification of sever and complicated acute pancreatitis prompts the highly dependent intensive care and early intervention. Gall stones are considered most common etiological factor for acute pancreatitis in India but alcoholism crosses this limit suggests changing life style of our people. Outcome is favourable in expectant conservative management of any form of acute pancreatitis.

Metrics

Metrics Loading ...

References

Banks PA. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 1997.92:377-86.

Tao HQ, Zhang JX, Zou SC. Clinical characteristics and management of patients with early acute severe pancreatitis: experience from a medical center in China. World J Gastroenterol. 2004;10(6):919..

Buter A, Imrie CW, Carter CR, Evans S, McKay CJ. Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis. Br J Surg. 2002;89(3):298-302.

Kong L, Santiago N, Han TQ, Zhang SD. Clinical characteristics and prognostic factors of severe acute pancreatitis. World J Gastroenterol. 2004;10(22):3336.

Hirano T, Manabe T. A possible mechanism for gallstone pancreatitis: repeated short-term pancreaticobiliary duct obstruction with exocrine stimulation in rats. Proceed Soci Exp Biol Med. 1993;202(2):246-52.

Norman J. Role of cytokines in the pathogenesis of acute pancreatitis. Am J Surg. 1998;175(1):76-83.

Narender NR, Pappu KP. A clinical study of acute pancreatitis. Int Surg J. 2016;3(1):96-100.

Vengadakrishnan K, Koushik AK. A study of the clinical profile of acute pancreatitis and its correlation with severity indices. Int J Health Sci. 2015;9(4).

Negi N, Mokta J, Sharma B, Sharma R, Jhobta A, Bodh V, et al. Clinical profile and outcome of acute pancreatitis: a hospital-based prospective observational study in Subhimalayan State. J Assoc Phys India. 2018;66(3):22-4.

Prasad HL, Nagarjuna TR. Clinical profile of patients with Acute pancreatitis. Int Surg J. 2016;4(7):2994-7.

Baig SJ, Rahed A, Sen S. A prospective study of the aetiology, severity and outcome of acute pancreatitis in Eastern India. Trop Gastroenterol. 2008;29(1):20-2.