DOI: http://dx.doi.org/10.18203/2349-2902.isj20220624

Clinico-pathological study of craniopharyngioma

Mohammed Sikandar, G. Venugopal, M. Srinivas Reddy

Abstract


Background: Craniopharyngioma is a tumour of the suprasellar region that histologically has two distinct variants with some differences in clinical behaviour. The papillary type is almost always seen in adults and has a more indolent course. We studied clinical and radiological characteristics, surgical resectability, clinical outcome and recurrence patterns in tertiary care center.

Methods: The present study is a prospective study, comprising of 32 patients of craniopharyngiomas studies over a period of 3 years. All the patients were thoroughly evaluated for the symptoms and signs with particular stress on visual impairment and field defects.

Results: There were 16 male and 16 female patients. The incidence of craniopharyngioma was observed more in the age group of 6-10 years. Fundoscopy examination revealed optic atrophy and papilloedema in (56.25%) eases. Endocrinological dysfunction were present in 31.25% cases. Appearance on computed tomography (CT) scan showed 31.25% as cystic and 68.75% was mixed respectively. Surgical approach to the tumor was through pterional approach in (75%) sub frontal in (18.75%) transphenoidal in 18.75%. There was 2 death, 10 patients were advised postoperative radiotherapy and follow up period was from 6 months to 2 years. There were 6 recurrences out of 32 patients who were under follow-up.

Conclusions: Treatment should focus not only on long term control and survival, but also on the reduction of the disease and related morbidity and preservation of quality of life.


Keywords


Craniopharyngiomas, Hydrocephalus, Endocrinological abnormalities, Pterional approach

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