DOI: https://dx.doi.org/10.18203/2349-2902.isj20220398
Published: 2022-02-28

Prevalence of Helicobacter pylori infection by rapid urease test among patients with dyspeptic symptoms who underwent upper gastrointestinal endoscopy in a secondary care hospital

Sudarshana Sreramaseshadri R. M., Shashidhara P.

Abstract


Background: Functional dyspepsia is referred to wide spectrum of upper gastrointestinal symptoms which are nonspecific and without organic pathology of upper gastrointestinal tract, and accounts for >60% of patients undergoing upper gastrointestinal endoscopy. The aim of our study was to determine the prevalence of active Helicobacter pylori (H. pylori) infection by retrospective review of patient records using only rapid urease test reports which gives us the magnitude of the H. pylori prevalence.

Methods: 200 patients who presented with dyspepsia were studied clinically according to the proforma over a period of 18 months from April 2020 to October 2021, Patients underwent upper gastro-intestinal endoscopy under topical anesthesia, and biopsies were taken from the antrum. Biopsy specimens were immediately placed onto rapid urease test kit containing urea and an indicator. Positive test for H. pylori was confirmed by the change in color of the medium from yellow to pink or red and when the rapid urease test was positive, patient was considered as H. pylori positive.

Results: Out of 200 patients, most commonly affected age group are patients between 18-35years and is more in males than females (48:36), 86 patients were found to be H. pylori positive (43%) associated with acid peptic disease and duodenal ulcers, gastric antral ulcers.

Conclusions: H. pylori is a potential risk factor of gastric malignancy. After being aware of the prevalence of H. pylori by early detection of active H. pylori infections, rapid urease test serves only as a rapid screening tool in dyspeptic symptoms of patients with acid peptic disease than all other tests.


Keywords


Prevalence, Dyspepsia, upper gastrointestinal endoscopy, Helicobacter pylori, rapid Urease test.

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