Prognostic value of neutrophil to lymphocyte ratio in acute gall stone and alcoholic pancreatitis


  • Sheeja Varghese Department of General Surgery, St. John’s Medical College, Bangalore, Karnataka, India
  • Anthony Prakash Rozario Department of General Surgery, St. John’s Medical College, Bangalore, Karnataka, India
  • Giridhar Ashwath Department of General Surgery, St. John’s Medical College, Bangalore, Karnataka, India
  • Sherlyn Ambrose Department of General Surgery, St. John’s Medical College, Bangalore, Karnataka, India



Acute pancreatitis, Neutrophil to lymphocyte ratio, Gall stone pancreatitis, Severity


Background: Acute pancreatitis (AP) is associated with increased mortality. Many scoring systems have been used to predict the severity of acute pancreatitis but they are either time consuming or done after 48 hours of admission. The aim of the study was to evaluate the prognostic value of Neutrophil to lymphocyte ratio (NLR) in acute gall stone and alcoholic pancreatitis.

Methods: 240 patients with acute pancreatitis were prospectively enrolled from December 2017 to December 2019 from the department of general surgery and gastroenterology at St. John’s Medical College, Bangalore. NLR obtained at admission were compared with other known prognostic scoring systems.

Results: A total of 240 patients were studied with an etiology of gall stone (N=131) and alcohol (N=109). NLR (17.6±18.3 vs 8.7±8.4, p<0.001) were significantly high in gall stone pancreatitis group whereas high NLR were not related to severe AP in alcoholic AP. For gall stone pancreatitis group NLR demonstrated a predictive value and not in alcoholic AP.

Conclusions: NLR can be used as a predictor of severity of acute pancreatitis, at the time of initial diagnosis. Our study demonstrated that NLR can predict the severity in gall stone pancreatitis.



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Original Research Articles