Thyroid lipomatosis in a patient of post renal transplantation
DOI:
https://doi.org/10.18203/2349-2902.isj20220965Keywords:
Lipomatosis, Benign, Goiter, Case reportAbstract
Thyroid lipomatosis is a rare benign disease with very few cases available in literature. We report a case of a 48 year old Indian male who presented with progressive swelling in front of neck since 5 years and difficulty breathing in lying down position along with difficulty in swallowing for the last 2 months. He is a known case of post renal transplantation for chronic kidney disease due to secondary AA amyloidosis. Total thyroidectomy was done and histopathology showed diffuse thyroid lipomatosis, with no evidence of amyloid deposition or papillary carcinoma. Fatty tissue is not commonly detected within the thyroid gland. Here we have reviewed the literature and discussed various differential diagnosis of thyroid lipomatosis.
References
Sanuvada RV, Chowhan AK, Rukmangadha N, Patnayak R, Yootla M, Amancharla LY. Thyrolipomatosis: an inquisitive rare entity. Gland Surg. 2014;3(4):E6-9.
Kitagawa W, Kameyama K, Tamai S. Adenolipoma of the thyroid gland: report of a case. Surg Today. 2004;34:593-6.
Arslan A, Alı́ç B, Uzunlar AK, Büyükbayram H, Sarı́ I. Diffuse lipomatosis of thyroid gland. Auris Nasus Larynx. 1999;26(2):213-5.
Bell S, Sosa GA, Del Valle Jaen A, Picasso MF. Thyroid lipomatosis in a 36-year-old patient with rheumatoid arthritis and a kidney transplant. Endocrinol Diabetes Metab Case Rep. 2016;2016(1):160007.
Breek JK, Vallaeys JH, Rutsaert RR. Simultaneous presentation of a thyrolipoma and a thymolipoma in a young man. Eur J Surg. 1997;163(12):941-3.
Schröder S, Böcker W. Lipomatous lesions of the thyroid gland: a review. Appl Pathol. 1985;3(3):140-9.
Livolsi, Virginia A. Surgical pathology of the thyroid. WB Saunders company. 1990;22.
Lau E, Freitas P, Costa J, Batista R, Máximo V, Coelho R et al. Loss of mitochondrial SDHB expression: what is its role in diffuse thyroid lipomatosis? Horm Metab Res. 2015;47(3):165-7.
Gonulalan G, Esen H, Erikoğlu M, Cakir M. Thyroid lipomatosis. Intern Med. 2012;51(24):3383-5.
Ryan L, Carolyn D. Diffuse Lipomatosis of the Thyroid Gland. Ultrasound Q. 2013;29(3):253-4.
Ge Y, Luna MA, Cowan DF, Truong LD, Ayala AG. Thyrolipoma and thyrolipomatosis: 5 case reports and historical review of the literature. Ann Diagn Pathol. 2009;13(6):384-9.
Dhayagude RG. Massive fatty infiltration in a colloid goiter. Arch Pathol Lab Med. 1942; 33: 357-60.
Jacques TA, Stearns MP. Diffuse lipomatosis of the thyroid with amyloid deposition. J Laryngol Otol. 2013;127(4):426-8.
Meningaud JP, Pitak-Arnnop P, Bertrand JC. Multiple Symmetric Lipomatosis: Case Report and Review of the Literature. J Oral Maxillofac Surg. 2007;65(7):1365-9.