Clinical profile and management of chronic pancreatitis in tertiary care centre
DOI:
https://doi.org/10.18203/2349-2902.isj20221144Keywords:
Chronic pancreatitis, Alcohol, PseudocystAbstract
Background: Chronic pancreatitis is a multifactorial disease, with a wide range of symptoms and geographic variation. Aim of this study is to study clinical profile and management of chronic pancreatitis with respect to demography, clinical findings, lab parameters, imaging investigations and management modalities.
Methods: A cross sectional observational study was conducted which included the patients admitted in tertiary care centre presenting with clinical diagnosis of chronic pancreatitis. The study was conducted over period of 2 years from November 2019 to October 2021. A total sample size of 71 patients were included.
Results: In the study, it was observed that majority of patients in age group of 51-60 years which were male (76.06%). Alcoholism (43.66%) was most common etiology and presented with pain in abdomen (85.92%). In the present study, majority of patients were managed conservatively (43.66%).The distribution of patients according to pain relief by various management showed that majority of get relief of pain by surgery (69.23%).
Conclusions: Chronic pancreatitis is progressive inflammatory disease. Alcoholic pancreatitis being most common etiology. Pain is most common presenting symptom. CT-SCAN abdomen most useful in confirming diagnosis in our set up. Pseudocyst being common complication seen. Surgery gives relief of pain in most of the cases.
References
Ramesh H. Tropical Pancreatitis. Ind J Gastroenterol. 1997;16:20-5.
Prabha S, Peeyush M. Chronic pancreatitis-Indian Scenario. 2005;5:418-424.
Garg PK, Tondon RK. Survey on chronic pancreatitis in the Asia-Pacific region. J Gastro-enterol Hepatol. 2004;19:998-1004.
Singhvi A, Yadav D. Myths and realities about alcohol and smoking in chronic pancreatitis. Curr Opin Gastroenterol. 2018;34(5):355-61.
Pham A, Forsmark C. Chronic pancreatitis: review and update of etiology, risk factors, and manage ment. F1000Res. 2018;7:45-9.
Beyer G, D'Haese JG, Ormanns S, Mayerle J. Chronic Pancreatitis and Pancreatic Cancer - Tumor Risk and Screening. Dtsch Med Wochenschr. 2018;143(12):895-906.
Anand BS. Clinical profile of chronic pancreatitis in Delhi. In: Balakrishnan V, ed. Chronic pancreatitis in India. Indian Soc Pancreatol. 1987:15-22.
Machicado JD. A population-based evaluation of the natural history of chronic pancreatitis. Pancreatol. 2018;18(1):39-45.
Noia JL. Morphological and functional changes of chronic pancreatitis in patients with dyspepsia: A prospective, observational, cross-sectional study. Pancreatol. 2018;18:280-5.
Hari SS, Raj RS. Chronic pancreatitis and its management in Thanjavur medical college hospital. Int J Conntemp Med Res. 2017;4(10):2118-22.
Panda CR, Misra B, Behera SK, Das HS, Singh SP. A Study on Changing Clinical Profile of Chronic Pancreatitis from a Tertiary Care Centre. Int J Sci Stud. 2017;5(4):170-3.
Ammann RW, Largiadèr F, Akovbiantz A: Pain relief by surgery in chronic pancreatitis? Relationship between pain relief, pancreatic dysfunction, and alcohol withdrawal. 1979;14(2):209-15.
Sharma R, Pradhan B, Karki P, Subedi M. Clinical and Epidemiologic Profile of Chronic Pancreatitis, A Retrospective Study in Eastern Nepal. J Adv Int Med. 2018;7(2):30-3.
Bhasin DK, Singh G, Rana SS, Chowdry SM, Shafiq N, Malhotra S, et al. Clinical profile of idiopathic chronic pancreatitis in North India. Clin Gastroenterol Hepatol. 2009;7(5):594-9.
Ali UA, Pahlplatz JM, Nealon WH, van Goor H, Gooszen HG, Boermeester MA. Endoscopic or surgical intervention for painful obstructive chronic pancreatitis. Cochrane Database Syst Rev. 2015;3:11-5.
Issa Y, Kempeneers MA, Bruno MJ, Fockens P, Poley JW, Ali UA, et al. Effect of early surgery vs endoscopy-first approach on pain in patients with chronic pancreatitis: the ESCAPE randomized clinical trial. JAMA. 2020;323(3):237-47.
Traverso LW, Longmire WP. Preservation of the pylorus in pancreaticoduodenectomy a follow-up evaluation. Annal Surg. 1997;192(3):306.
Cahen DL, Gouma DJ, Laramée P, Nio Y, Rauws EA, Boermeester MA, et al. Long-term outcomes of endoscopic vs surgical drainage of the pancreatic duct in patients with chronic pancreatitis. Gastro-enterol. 2011;141(5):1690-5.
