Retrospective analysis of etiological factors and clinical presentation of pancreatitis in patients of a tertiary care hospital
DOI:
https://doi.org/10.18203/2349-2902.isj20220319Keywords:
Clinical presentation, Acute pancreatitis, EtiologyAbstract
Background: Acute pancreatitis is a complicated illness with a wide range of local and systemic consequences that surgeons throughout the world deal with. This study evaluated the etiology and clinical presentation of acute pancreatitis patients retrospectively in a tertiary health care center.
Methods: This study is a cross-sectional, retrospective hospital-based study that was conducted from Feb 2012 to Feb 2020 which was conducted on 500 patients who had acute pancreatitis in the department of general surgery and gastroenterology in a tertiary health care center.
Results: Out of the total of 500 patients, 75% of males had acute pancreatitis and 25% of females had acute pancreatitis. The 52% of the patients had epigastric pain without radiating to the back and it was the most common clinical presentation followed by 30% of the patients had epigastric pain radiating to the back followed by generalized abdominal pain (18%). Nausea and vomiting were observed in most of the cases (71%). Alcohol-induced pancreatitis was the most common (41.2%) among the 500 cases, followed by idiopathic pancreatitis (36.2%). The acute fluid collection was identified in 26.6% of cases. The most prevalent systemic consequence was respiratory system involvement (15%).
Conclusions: The most common clinical manifestation was epigastric pain with no radiation to the back. In our study, the incidence of alcoholic pancreatitis (41.2%) and idiopathic pancreatitis (36.2%) was slightly greater, prompting us to look for additional aetiologies in the idiopathic category in future investigations.
Metrics
References
Lowenfels AB, Maisonneuve P, Sullivan T. The changing character of acute pancreatitis: epidemiology, etiology, and prognosis. Curr Gastroenterol Rep. 2009;11(2):97e-103.
Kingsnorth A, O'Reilly D. Acute pancreatitis. BMJ. 2006;332(7549):1072e-6.
McKay CJ, Imrie CW. The continuing challenge of early mortality in acute pancreatitis. Br J Surg. 2004;91(10):1243e-4.
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international consensus. Gut BMJ. 2013;62:102-11.
Sakorafas GH, Tsiotou AG. Etiology and pathogenesis of acute pancreatitis: current concepts. J Clin Gastroenterol. 2000;30(4):343e-56.
Ramu R, Vergis Paul, Devipriya S, Philip NC. Etiology, clinical profile and outcome of acute pancreatitis in a tertiary care teaching hospital in rural South India: a ten-year retrospective study. Int Surg J. 2019;6(10):3794-9.
Lee MG, Chung A, Miles A, Terry SI, Royes CA. Chronic pancreatitis in Jamaica. West Indian Med J. 1992;41:61-3.
Vengadakrishnan K, Koushik AK. A study of the clinical profile of acute pancreatitis and its correlation with severity indices. Int J Health Sci (Qassim). 2015;9(4):410-7.
Casas JD, Díaz R, Valderas G, Mariscal A, Cuadras P. Prognostic value of CT in the early assessment of patients with acute pancreatitis. Am J Roentgenol. 2004;182(3):569-74.
Barreto SG, Tiong L, Williams R. Drug-induced acute pancreatitis in a cohort of 328 patients. A single-centre experience from Australia. JOP J Pancreas. 2011;12(6):581-5.
Raghuwanshi S, Gupta R, Vyas MM, Sharma R. CT Evaluation of Acute Pancreatitis and its Prognostic Correlation with CT Severity Index. J Clin Diagnos Res. 2016;10(6):TC06-11.
Reid GP, Williams EW, Francis DK, Lee MG. Acute pancreatitis: A 7-year retrospective cohort study of the epidemiology, aetiology and outcome from a tertiary hospital in Jamaica. Ann Med Surg (Lond). 2017;20:103-8.
Banday IA, Gattoo I, Khan AM, Javeed J, Gupta G, Latief M. Modified computed tomography severity index for evaluation of acute pancreatitis and its correlation with clinical outcome: a tertiary care hospital based observational study. J Clin Diagnos Res. 2015;9(8):TC01.
Ahlawat V, Godara R. Clinical study of demographic Profile, Etiology, Severity and Outcome of Acute Pancreatitis in a Tertiary Care Teaching Hospital in Northern India. J Gastrointest Dig Syst. 2018;8:575.
Nesvaderani M, Guy D, Vagg ED, Faraj S, Cox MR. Epidemiolody, aetiology and outcomes of acute pancreatitis: A retrospective cohort study. Int J Surg. 2015;23;68-74.