Granulomatous fat necrosis of breast a diagnostic dilemma: a rare case report

Authors

  • Aswin Mukesh Department of General Surgery, Mahatma Gandhi medical college and research institute, Pillaiyarkuppam, Pondicherry, India
  • Murugan A. Department of General Surgery, Mahatma Gandhi medical college and research institute, Pillaiyarkuppam, Pondicherry, India
  • Rajan K. V. Department of General Surgery, Mahatma Gandhi medical college and research institute, Pillaiyarkuppam, Pondicherry, India

DOI:

https://doi.org/10.18203/2349-2902.isj20220652

Keywords:

Tuberculous mastitis, Breast, Carcinoma breast, Tuberculosis, Breast lump

Abstract

Fat necrosis in breast is a rare benign condition, which can mimic carcinoma and Tuberculosis (TB) of breast in both clinical and radiological assessment. Histopathology in such cases may distinguish granulomatous lesion from carcinoma, however granulomas are identified in both fat necrosis and tuberculosis which is difficult to differentiate. Fat necrosis in breast is often not associated with axillary lymph nodes, which can differentiate fat necrosis from tuberculosis and breast carcinoma. But high index of suspicion is always required. We hereby report a case of a 40-year old female, who presented with lump in the right breast which lead to diagnostic dilemma.

References

Kumar R, Laxman S, Parandekar P. Breast lump: A rare presentation of tuberculosis. Int J App Basic Med Res. 2018;8(3):187.

Baharoon S. Tuberculosis of the breast. Ann Thorac Med. 2008;3(3):110.

Kerridge WD, Kryvenko ON, Thompson A, Shah BA. Fat Necrosis of the Breast: A Pictorial Review of the Mammographic, Ultrasound, CT, and MRI Findings with Histopathologic Correlation. Radiology Research and Practice. 2015;2015:1-8.

Illman JE, Terra SB, Clapp AJ, Hunt KN, Fazzio RT, Shah SS, et al. Granulomatous diseases of the breast and axilla: radiological findings with pathological correlation. Insights Imaging. 2018;9(1):59-71.

Mirsaeidi SM, Masjedi MR, Mansouri SD, Velayati AA. Tuberculosis of the breast: report of 4 clinical cases and literature review. East Mediterr Health J. 2007;13(3):670-6.

Khandelwal R, Jain I. Breast tuberculosis mimicking a malignancy: a rare case report with review of literature. Breast Dis. 2013;34(2):53-5.

Thimmappa D, Mallikarjuna MN, Vijayakumar A. Breast Tuberculosis. Indian J Surg. 2015;77(Suppl 3):1378-84.

Sriram K, Moffatt D, Stapledon R. Tuberculosis infection of the breast mistaken for granulomatous mastitis: a case report. Cases J. 2008;1:273.

Marinopoulos S, Lourantou D, Gatzionis T, Dimitrakakis C, Papaspyrou I, Antsaklis A. Breast tuberculosis: Diagnosis, management and treatment. International Journal of Surgery Case Reports. 2012;3(11):548-50.

Baykan AH, Sayiner HS, Inan I, Aydin E, Erturk SM. Primary breast tuberculosis: imaging findings of a rare disease. Insights Imaging. 2021;12(1):19.

Khurram M, Tariq M, Shahid P. Breast cancer with associated granulomatous axillary lymphadenitis: a diagnostic and clinical dilemma in regions with high prevalence of tuberculosis. Pathol Res Pract. 2007;203(10):699-704.

Teo THP, Ho GH, Chaturverdi A, Khoo BKJ. Tuberculosis of the chest wall: unusual presentation as a breast lump. Singapore Med J. 2009;50(3):e97-99.

Downloads

Published

2022-02-28

Issue

Section

Case Reports