Epidemiological, demographic and risk factor profile in patients harbouring various types of gallbladder calculi: a cross sectional study from a south Indian tertiary care hospital
DOI:
https://doi.org/10.18203/2349-2902.isj20164794Keywords:
Cholesterol, Gallstones, ObesityAbstract
Background: Gallstone disease is one of the most common digestive system diseases next to GERD and accepted treatment involves laparoscopic or open cholecystectomy making it one of the costly diseases. with increasing westernisation of Indian lifestyle and food and also recent studies pointing out its association with cardiovascular disease and cancer mortality its need of the time to undertake an extensive study on epidemiology, demography and risk factors of gallstone disease. The aim was to study the epidemiological, demographic and risk factor profile in patients harbouring various types of gallbladder calculi.
Methods: A cross sectional prospective study was conducted. 100 cholelithiasis patients were undergoing operative procedure at our department.
Results: Showed that females had higher incidence of gallstone disease with a ratio of 2:1, mixed gallstone was the predominant type (53%), mean BMI of the study population was 28.03 with SD of 3.61.
Conclusions: Women are twice as likely as men to form gallstones. Most common gallstone type found is mixed type and least is cholesterol type. Age group most commonly affected is between 31-50 years. There is a statistically significant association between high BMI and occurrence of gallstone. There is a statistically significant association between diabetes and occurrence of gallstone.
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References
Carey MC, Paigen B. Epidemiology of the American Indians' burden and its likely genetic origins. Hepatol. 2002;36(4):781-91.
Schafmayer C, Hartleb J, Tepel J. Predictors of gallstone composition in 1025 symptomatic gallstones from Northern. BMC Gastroenterol. 2006;6:36.
Pundir CS, Chaudhary R, Rani K, Chandran P, Kumari M, Garg P. Chemical analysis of biliary calculi in Haryana. Ind J Surg. 2001;63:370-3.
Tyagi SP, Tyagi N, Maheshwari V, Ashraf SM, Sahoo P. Morphological changes in diseased gall bladder: a study of 415 cholecystectomies at Aligarh. J Ind Med Assoc. 1992;90:178-81.
Bansal SK, Gupta SK, Bansal A, Rajput VS, Joshi LD. Chemical composition of biliary calculi from Kanpur region. Ind J Clin Biochem. 1992;7:27-9.
Goswami M. An analysis of 160 cholecystectomies at Guwahati. Ind J Surg. 1999;61:252-5.
Nakayama F. Quantitative microanalysis of Gallstones. J Lab Clin Med. 1968;72:602-11.
Olokoba AB, Bojuwoye BJ, Katibi IA. Relationship between gallstone disease and serum lipids in normal adult Nigerians. African Scientist. 2006;7(3):113-6.
Stampfer M, Maclure K, Colditz G. Risk of symptomatic gallstones in women with severe obesity. Am J Clin Nutr. 1992;55(3):652-8
Ruhl CE, Everhart JE. Association of diabetes, serum insulin, and C-peptide with gallbladder disease. Hepatology. 2000;31:299-303.