Published: 2022-05-26

Clinico-pathological study of cervical lymph nodes in children using ultrasound scan and FNAC: a hospital-based study

G. V. Ramana Reddy, M. Mallikharjuna Reddy, Mittakanti Jawali Reddy, Dussa Prashanth


Background: Cervical lymphadenopathy is one of the commonest clinical diagnostic dilemmas in children. The diagnosis plays key role in the management of cervical lymphadenopathy. Various methods of diagnosis include non-invasive and invasive procedures. Ultrasonography is a non-invasive readily available investigation for evaluation of cervical lymph nodes. One of the most reliable, less expensive diagnostic procedure is fine needle aspiration cytology (FNAC).

Methods: A prospective study was conducted on 150 children in SVS Medical College Hospital, Mahabubnagar   between January 2017 and January 2020. Ultrasonography followed by FNAC of lymph node was done in all children. Microsoft office excel software used for the data analysis. Sample size was calculated with 85% confidence level and 5% margin of error.

Results: Out of 150 patients 79 were non-specific reactive lymphadenitis. 54 were granulomatous lymphadenitis.15 were lymphomas. 2 were malignant.

Conclusions: Both ultrasonography and FNAC are very useful tools in the evaluation of cervical lymphadenopathy in children.  


Cervical lymphadenopathy, Ultrasonography, FNAC, Children

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Shaha A, Webber C, Marti J. Fine-needle aspiration in the diagnosis of cervical lymphadenopathy. Am J Surg. 1986;152(4):420-3.

Pulgaonkar R, Chitra P, Moosvi Z. Benign reactive lymphadenopathy associated with submandibular gland enlargement during orthodontic treatment. J Oral Maxillofac Pathol. 2017;21(1):181.

Wright CA, Warren RM, Marais BJ. Fine needle aspiration biopsy: an undervalued diagnostic modality in paediatric mycobacterial disease. Int J Tuberc Lung Dis. 2009;13(12):1467-75.

Fontanilla JM, Barnes A, Reyn CF. Current diagnosis and management of peripheral tuberculous lymphadenitis. Clin Infect Dis. 2011;53(6):555-62.

Thuja A, Ying M. Sonographic Evaluation of Cervical Lymph Nodes. American J Roentgenol. 2005;184:1691-9.

Dulin MF, Kennard TP, Leach L, Williams R. Management of cervical lymphadenitis in children. Am Fam Physician. 2008;78(9):1097-8.

Pandey A, Kureel SN, Pandey J, Wakhlu A, Rawat J, Singh TB. Chronic cervical lymphadenopathy in children: Role of ultrasonography. J Indian Assoc Pediatr Surg. 2012;17(2):58-62.

Ahuja A, Ying M. Grey-scale sonography in assessment of cervical lymphadenopathy: review of sonographic appearances and features that may help a beginner. Br J Oral Maxillofac Surg. 2000;38(5):451-9.

Lee DH, Baek HJ, Kook H, Yoon TM, Lee JK, Lim SC. Clinical value of fine needle aspiration cytology in pediatric cervical lymphadenopathy patients under 12-years-of-age. Int J Pediatr Otorhinolaryngol. 2014;78(1):79-81.

Moore SW, Schneider JW, Schaaf HS. Diagnostic aspects of cervical lymphadenopathy in children in the developing world: a study of 1,877 surgical specimens. Pediatr Surg Int. 2003;19(4):240-4.

Park YW. Evaluation of neck masses in children. Am Fam Physician. 1995;51(8):1904-12.

Deosthali A, Donches K, Vecchio M, Aronoff S. Etiologies of Pediatric Cervical Lymphadenopathy: A Systematic Review of 2687 Subjects. Glob Pediatr Health. 2019;6:2333794.