Merkel cell carcinoma: a case report and literature review
DOI:
https://doi.org/10.18203/2349-2902.isj20213182Keywords:
Merkel cell carcinoma, Neuroendocrine carcinoma of the skin, Skin neoplasms, PolyomavirusAbstract
Merkel cell carcinoma (MCC) is a rare, but highly aggressive, malignant neuroendocrine tumor, with a higher prevalence in men, Caucasians, and the elderly. It is usually identified in photo-exposed areas such as the head, trunk, and extremities. It is related to locoregional recurrences and metastases, which conditions a high mortality rate. Currently, the pathogenesis is unclear, but it is related to ultraviolet radiation, immunosuppression, and polyomavirus infection. Prompt diagnosis and treatment are essential to improve the survival rate.
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