Published: 2021-08-27

Merkel cell carcinoma: a case report and literature review

Soulé-Martínez Christian Enrique, Monroy-Ramírez Miguel Angel, Jaimes-Durán Edwing Michel, Castellanos-Aguilar Leonel, Ricarte-Almeida Eros Rafael, Lupián-Angulo Arianne I.


Merkel cell carcinoma (MCC) is a rare, but highly aggressive, malignant neuroendocrine tumor, with a higher prevalence in men, Caucasians, and the elderly. It is usually identified in photo-exposed areas such as the head, trunk, and extremities. It is related to locoregional recurrences and metastases, which conditions a high mortality rate. Currently, the pathogenesis is unclear, but it is related to ultraviolet radiation, immunosuppression, and polyomavirus infection. Prompt diagnosis and treatment are essential to improve the survival rate.


Merkel cell carcinoma, Neuroendocrine carcinoma of the skin, Skin neoplasms, Polyomavirus

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