DOI: http://dx.doi.org/10.18203/2349-2902.isj20213143

Extra-pelvic endometriosis presenting as recurrent hepatic cyst: case report and literature review

Ruqia Mushtaq, Aqsa Ameer, Muhammad Hanif, Fatima Rauf

Abstract


Hepatic endometriosis is a very rare form of endometriosis first described by Rokitansky in 1986. To our knowledge, 42 cases of hepatic endometriosis have been reported in the literature till date. The condition offers a diagnostic challenge owing to its variable presentation on imaging and the need for histological and immunohistochemical evidence for a definite diagnosis. We hereby present the 43rd case of ectopic endometrium in the liver of a 30 years old, multiparous female who presented with fever and pain in the right hypochondrium. Radiological imaging suggested a cystic lesion which was managed laparoscopically. Histopathology and immunohistochemistry findings came out to be consistent with endometriosis. The case highlighted the importance of considering endometriosis as a differential in all women irrespective of age and previous history of endometriosis.


Keywords


Endometriosis, Cyst, Hepatic endometriosis, Liver endometriosis, Case report

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References


Charatsi D, Koukoura O, Ntavela IG, Chintziou F, Gkorila G, Tsagkoulis M, et al. Gastrointestinal and Urinary Tract Endometriosis: A Review on the Commonest Locations of Extra-pelvic Endometriosis. Advan Med. 2018;3461209.

Markham SM. In: Modern Approaches to Endometriosis. Thomas EJ, Rock JA, eds. Extra-pelvic endometriosis. Dordrecht: Springer; 1991.

Bohra AK, Diamond T. Endometrioma of the liver. International journal of clinical practice. Mohling S. Hepatic Endometriosis. J Minimally Invasive Gynecol. 2001;55(4):286-7.

Mohling S. Hepatic Endometriosis. Journal of Minimally Invasive Gynecology. 2020;27(7):31.

Baniak N, Adams S, Chibbar R, Lee CH, Kanthan R. Hepatic endometrial stromal sarcoma. Pathol Res Practice. 2018;214(10):1726-31.

Khan AW, Craig M, Jarmulowicz M, Davidson BR. Liver tumours due to endometriosis and endometrial stromal sarcoma. J Int Hepato Pancreato Biliary Association. 2002;4(1):43-5.

N'senda P, Wendum D, Balladur P, Dahan H, Tubiana JM, Arrive L. Adenosarcoma arising in hepatic endometriosis. European Radiol. 2000;10(8):1287-9.

Sourial S, Tempest N, Hapangama DK. Theories on the Pathogenesis of Endometriosis. International J Reprod Med. 2014;179515.

Goldsmith PJ, Ahmad N, Dasgupta D, Campbell J, Guthrie JA, Lodge JP. Case hepatic endometriosis: a continuing diagnostic dilemma. HPB Surg. 2009;2009:407206.

Gupta HA, Agarwal A, Premkumar B, Yazar C, Kakaiya R. In: Role of Environmental Pollutants in Endometriosis. Endometriosis. Springer; 2015.

Burney RO, Giudice LC. Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2012;98(3):511-9.

Prodromidou A, Machairas N, Paspala A, Hasemaki N, Sotiropoulos GC. Diagnosis, surgical treatment and postoperative outcomes of hepatic endometriosis: A systematic review. Annals of Hepatol. 2020;19(1):17-23.

Grabb A, Carr L, Goodman JD, Mendelson DS, Cohen B, Finkel L. Hepatic endometrioma. Journal of clinical ultrasound : JCU. 1986;14(6):478-80.

Rovati V, Faleschini E, Vercellini P, Nervetti G, Tagliabue G, Benzi G. Endometrioma of the liver. American J Obstet Gynecol. 1990;163(5):1490-2.

Cravello L, Ercole C, Treut YP, Blanc B. Hepatic endometriosis: a case report. Fertil Steril. 1996;66(4):657-9.

Verbeke C, Härle M, Sturm J. Cystic endometriosis of the upper abdominal organs. Report on three cases and review of the literature. Pathol Re Practice. 1996;192(3):300-4.

Weinfeld RM, Johnson SC, Lucas CE, Saksouk FA. CT diagnosis of perihepatic endometriosis complicated by malignant transformation. Abdominal Imaging. 1998;23(2):183-4.

Chung C, Liew C, Hewitt P, Leung K, Lau W. Endometriosis of the liver. Surgery. 1998;123(1):106-8.

İnal M, Bıçakçı K, Soyupak S, Oğuz M, Özer C, Demirbaş Ö, et al. Hepatic endometrioma: a case report and review of the literature. European Radiol 2000;10(3):431-4.

Huang WT, Chen WJ, Chen CL, Cheng YF, Wang JH, Eng HL. Endometrial cyst of the liver: a case report and review of the literature. J Clin Pathol. 2002;55(9):715-7.

Leanes AC, Murray D, Davidson B, Hamilton M, Watkinson AF. Hepatic and Retro-peritoneal Endometriosis Presenting as Obstructive Jaundice with Ascites: A Case Report and Review of the Literature. Clinical Radiol. 2002;57(3):226-9.

Tuech JJ, Rousselet MC, Boyer J, Descamps P, Arnaud JP, Ronceray J. Endometrial cyst of the liver: case report and review. Fertil Steril. 2003;79(5):1234-6.

Reid GD, Kowalski D, Cooper MJ, Kaloo P. Hepatic endometriosis: a case report and review of the literature. Australian and New Zealand J obstetr Gnaecol. 2003;43(1):87-9.

Steele JA, Jorge A, Catania M, Foster S. Hepatic Endometriosis: A Sonographic Demonstration. J Diagnostic Med Sonograp. 2003;19(3):184-7.

Groves A, Whitfield R, Lomas D, Gibbs P. Imaging of a hepatic endometrioma in a patient with multiple haemangiomas. J Hepatol. 2003;38:547.

Girlanda R, Howard ER, Heaton ND. Peri-hepatic endometriosis. Int J Gynaecol Obstet. 2005;88(3):338-9.

Goldsmith PJ, Ahmad N, Dasgupta D, Campbell J, Guthrie JA, Lodge JPA. Case hepatic endometriosis: a continuing diagnostic dilemma. HPB Surg. 2009;407206.

Asran M, Rashid A, Szklaruk J. Hepatic endometriosis mimicking metastatic disease: a case report and review of the literature. J Radiol Case Rep. 2010;4(11):26-31.

Dietlen F, Jiménez GA, Pérez MA, Grube PP, Ramírez-Cervantes KL, Remes-Troche JM. Hepatic endometriosis. Ann Hepatol. 2011;10(3):347-8.

Schuld J, Justinger C, Wagner M, Bohle RM, Kollmar O, Schilling MK, Richter S. Bronchobiliary fistula: a rare complication of hepatic endometriosis. Fertil Steril. 2011;95(2):804-15.

Fluegen G, Jankowiak F, Zacarias FL, Kroepil F, Knoefel WT, Topp SA. Intrahepatic endometriosis as differential diagnosis: case report and literature review. World J Gastroenterol. 2013;19(29):4818-22.

Rivkine E, Jakubowicz D, Marciano L, Polliand C, Poncelet C, Ziol M, et al. Hepatic endometrioma: a case report and review of the literature: report of a case. Surgery Today. 2013;43(10):1188-93.

Hertel JD, Guimaraes M, Yang J. Hepatic endometriosis diagnosed by liquid-based cytology: a case report. Diagnostic cytopathol. 2014;42(5):441-4.

Theodosopoulos T, Yiallourou AI, Hatzipappas J, Koutoulidis V, Dadnios N, Contis J. Right-shoulder pain: an unusual sign of hepatic endometriosis. J Gynecol Surg. 2014;30(6):383-5.

Liu K, Zhang W, Liu S, Dong B, Liu Y. Hepatic endometriosis: a rare case and review of the literature. Eur J Med Res. 2015;20(1):48.

Sopha SC, Rosado FG, Smith JJ, Merchant NB, Shi C. Hepatic uterus-like mass misdiagnosed as hepatic abscess. In J Surgical Pathol. 2015;23(2):134-9.

Riggi MA, Fusco F, Marino G, Izzo A. Giant endometrial cyst of the liver: a case report and review of the literature. Il Giornale di chirurgia. 2016;37(2):79-83.

Sherif AM, Musa ER, Kedar R, Fu L. Subcapsular hepatic endometriosis: case report and review of the literature. Radiol Case Report. 2016;11(4):303-8.

Keramidaris D, Gourgiotis S, Koutela A, Mpairamidis E, Oikonomou C, Villias C, et al. Rare Case of Hepatic Endometriosis as an Incidental Finding: Difficult Diagnosis of a Diagnostic Dilemma. Ann Hepatol. 2018;17(5):884-7.

Manwani B, Shobassy M, Hair C. Hepatic Endometrioma: A Rare Case of an Intraparenchymal Endometriosis of the Liver: 2387. Official J American College Gastroenterol. 2018;113:1332-3.

Eychenne C, Suc B, Delchier MC, Vidal F, Rimailho J, Illac C, Breibach F, et al. Hepatic pedicle endometriosis: Case report and review of the literature. J Obstet Gynaecol Res. 2019;45(10):2121-7.