Leiomyoma an uncommon benign esophageal tumor

Ambreen Abid, Tanveer Ahmad, Misauq Mazcuri, Nazish Sikander


Leiomyoma are rare esophageal masses. Majority remain asymptomatic but may present with dysphagia when more than five centimeters in size. Barium swallow is the initial diagnostic investigation. Small lesion can be observed. Symptomatic and large lesion should undergo prompt surgical enucleation. Here we presented a case of a 35 year old female presenting with progressive dysphagia and gradual weight loss for 5 years along with regurgitation for one year. Clinical examination was unremarkable. Barium study was suggestive of smooth intramural defect with normal mucosa. Computed tomography showed well defined homogenous opacity located intramuraly at the level of junction of middle and distal third of esophagus with normal surrounding structures. Surgical enucleation was done through a right posterolateral thoracotomy. Muscle defect was repaired and checked for possible leaks. Liquid diet was commenced on 5th postoperative day. Patient was discharged on semisolid diet for two weeks with progression to solid meal.


Leiomyoma, Esophageal masses, Enucleation

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Rao M, Meng Q, Gao P. Large leiomyoma of lower esophagus diagnosed by endoscopic ultrasonography–fine needle aspiration: a case report. World J Clinic Cases. 2020;8(22):5809-15.

Yalçınkaya İ. Clinical outcomes in the surgical treatment of esophageal leiomyoma: a retrospective evaluation of 13 cases. Turkish J Thoracic Cardiovascul Surg. 2020;28(3):505-13.

Yankov G, Mekov E, Getsov P, Churchev S, Golemanov B, Kovacheva-Slavova M, et al. Diagnosis And surgical treatment of esophageal leiomyoma. Int J Med Sci Clinic Invent. 2020;7(6):4837-40.

Sun X, Wang J, Yang G. Surgical treatment of esophageal leiomyoma larger than 5 cm in diameter: a case report and review of the literature. J Thoracic Dis. 2012;4(3):323-6.

Zhou S, Li S, Guo N, Zhang W. A case of surgical enucleation of a giant esophageal leiomyoma. Transl Surg 2017;2:19-21.

Aurea P. Giant leiomyoma of the esophagus. Euro J Cardio Thoracic Surg. 2002;22(6):1008-10.

Mathew G, Osueni A, Carter YM. Esophageal leiomyoma. Treasure Island (FL): StatPearls Publishing; 2021.

Asteriou C, Konstantinou D, Lalountas M, Kleontas A, Setzis K, Zafiriou G, et al. Nine years’ experience in surgical approach of leiomyomatosis of esophagus. World J Surg Oncol. 2009;7(1):102.