DOI: http://dx.doi.org/10.18203/2349-2902.isj20212277

Macroglossia and outcome of severity based treatment regime

Umesh Kumar, Vijaykumar Huded, Sudipta Bera, Pradeep Jain, Arnab Sarkar, Yasharth Sharma

Abstract


Background: This study aims to categorize macroglossia patients into mild, moderate, and severe groups and formulate a treatment plan depending upon the severity of tongue involvement.

Methods: Eight patients presented with macroglossia between 2018 and 2020 are reviewed retrospectively. The patients were categorized into three subgroups depending upon the clinical presentation and subjected to either sclerotherapy or surgical debulking. The clinical outcome as a reduction of size and symptomatic improvement were analyzed and categorized after a minimum of 6 months follow-up.

Results: Eight patients (5 males and 3 females) aged 10-40 years with a mean age of 28.25 (SD 10.29) years were included in the study. Of eight patients, four cases were of vascular malformation, three of neurofibroma, and one was due to amyloidosis. Four patients were treated with surgery, three with sclerotherapy while one patient was managed with combined modalities. On average, 58% and 28% volume reduction were achieved with surgery and sclerotherapy respectively. Excellent, very good, and good results were obtained in 1, 3, and 4 cases respectively. Pain (2/8), edema (2/8), and distal congestion (1/8) were noted as a complication.

Conclusions: Macroglossia results from various causes and the common cause being VM. Surgery and sclerotherapy are the mainstay treatment for such a condition. They remain effective when used alone or in combination and also in a staged manner depending upon the severity of macroglossia.


Keywords


Macroglossia, Severity, Key-hole, Sclerotherapy, Surgical debulking

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References


Prada CE, Zarate YA, Hopkin RJ. Genetic causes of macroglossia: diagnostic approach. Pediatrics. 2012;129:e431-7.

Wolford LM, Cottrell DA. Diagnosis of macroglossia and indications for reduction glossectomy. Am J Orthod Dentofacial Orthop. 1996;110:170-7.

Perkins JA.Overview of macroglossia and its treatment. Curr Opin Otolaryngol Head Neck Surg. 2009;17:460-7.

Vogel JE, Mulliken JB, Kaban LB: Macroglossia. a review of the condition and a new classification. Plast Reconstr Surg. 1986;78:715-23.

Okoro PE, Akadiri OA. Giant macroglossia with persistent nonoc-clusion in a neonate. Afr J Paediatr Surg. 2011;8:229-31.

Myer CM, Hotaling AJ, Reilly JS. The diagnosis and treatment of macroglossia in children. Ear Nose Throat J. 1986;65:444-8.

Balaji SM. Reduction glossectomy for largetongues. Ann Maxillofac Surg. 2013;3:167-72.

Kane WJ, Morris S, Jackson IT, Woods JE. Significant hemangiomas and vascular malformations of the head and neck: Clinical management and treatment outcomes. Ann Plast Surg. 1995;35:133-7.

Marocchio LS, Pereira MC, Soares CT, Oliveira DT. Oral plexiform neurofibroma not associated with neurofibromatosis type I: Case report. J Oral Sci. 2006;48:157.

Alatli C, Oner B, Unur M, Erseven G. Solitary plexiform neurofibroma of the oral cavity: A case report. Int J Oral Maxillofac Surg. 2006;25:379.

Gasparini G, Saltarel A, Carboni A, Maggiulli F, Becelli R. Surgical management of macroglossia: discussion of 7 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;94:566-70.

Usha V, Sivasankari T, Jeelani S, Asokan GS, Parthiban J. Lymphangioma of the tongue-a case report and review of literature. J Clin Diagn Res. 2014;8:12-4.

Wolford LM, Cottrell DA. Diagnosis of macroglossia and indications for reduction glossectomy. Am J Orthod Dentofacial Orthop. 1996;110:170-7.

Buckmiller LM, Richter GT, Suen JY. Diagnosis and management of hemangiomas and vascular malformations of the head and neck. Oral Dis. 2010; 16:405-18.

Xu J, Wang YF, Chen AW, Wang T, Liu SH. A modified Tessari method for producing more foam. Springer Plus. 2015;5:129.