Published: 2021-04-28

Lateral aberrant thyroid having papillary carcinoma: a case report

Saurabh Subhash Parab, Mansing N. Ghatage, Sharang S. Kulkarni, Aniket P. Patil, Pallavi S. Phatak, Apurva P. Hendre


Aberrant thyroid is a mass of tissue having the structure of a pathological thyroid gland situated at some definite distance from the normal thyroid gland. In all the variants of carcinoma of thyroid the papillary variant is the most common. Predominantly seen in females ranging in the age group of 25-45 years. It is often well differentiated, slow growing and localised. Here we report a case of a 35-year-old lady with a swelling in the right anterior triangle of the neck with normal thyroid gland. Histopathological report was suggestive of papillary carcinoma of thyroid. The origin of lateral ectopic thyroid tissue is not fully understood and controversial. The lateral localisation is a rare entity and debated extensively in the literature. Though rare, the possibility of an ectopic thyroid carcinoma must always be considered by the surgeon in cases of a pathological mass in the neck. This case report demonstrates that a normal thyroid gland on clinical examination does not exclude the presence of thyroid carcinoma in an ectopic tissue.


Aberrant thyroid, Carcinoma, Papillary carcinoma, Thyroid, Total thyroidectomy

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Escofet X, Khan AZ, Mazarani W, Woods WG. Lessons to be learned: a case study approach. Lateral aberrant thyroid tissue: is it always malignant? J R Soc Promot Health. 2007;127(1):45-6.

Babazade F, Mortazavi H, Jalalian H, Shahvali E. Thyroid tissue as a submandibular mass: a case report. J Oral Sci. 2009;51(4):655-7.

Nasiru Akanmu I, Mobolaji Adewale O. Lateral cervical ectopic thyroid masses with eutopic multinodular goiter: an unusual presentation. Hormones (Athens). 2009;8(2):150-3.

Jurayyan NA, el-Desouki MI. Transient iodine organification defect in infants with ectopic thyroid glands. Clin Nucl Med. 1997;22(1):13-6.

Shah BC, Ravichand CS, Juluri S, Agarwal A, Pramesh CS, Mistry RC. Ectopic thyroid cancer. Ann Thorac Cardiovasc Surg. 2007;13(2):122-4.

Abraham T, Schöder H. Thyroid cancer--indications and opportunities for positron emission tomography/computed tomography imaging. Semin Nucl Med. 2011;41(2):121-38.

Noussios G, Anagnostis P, Goulis DG, Lappas D, Natsis K. Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity. Eur J Endocrinol. 2011;165(3):375-82.

Klubo-Gwiezdzinska J, Manes RP, Chia SH, Burman KD, Stathatos NA, Deeb ZE, et al. Clinical review: Ectopic cervical thyroid carcinoma--review of the literature with illustrative case series. J Clin Endocrinol Metab. 2011;96(9):2684-91.

Lianos G, Bali C, Tatsis V, Anastasiadi Z, Lianou E, Papathanasiou V, Messinis T. Ectopic thyroid carcinoma. Case report. G Chir. 2013;34(4):114-6.

Kuffner HA, McCook BM, Swaminatha R, Myers EN, Hunt JL. Controversial ectopic thyroid: a case report of thyroid tissue in the axilla and benign total thyroidectomy. Thyroid. 2005;15(9):1095-7.

Choi JY, Kim JH. A case of an ectopic thyroid gland at the lateral neck masquerading as a metastatic papillary thyroid carcinoma. J Korean Med Sci. 2008;23(3):548-50.

Noussios G, Anagnostis P, Goulis DG, Lappas D, Natsis K. Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity. Eur J Endocrinol. 2011;165(3):375-82.

Caccetta TP, Kumar A, Ishak H. Lateral aberrant thyroid tissue presenting as a lateral neck mass. ANZ J Surg. 2005;75(12):1123-4.

Rahbar R, Yoon MJ, Connolly LP, Robson CD, Vargas SO, McGill TJ, Healy GB. Lingual thyroid in children: a rare clinical entity. Laryngoscope. 2008;118(7):1174-9.

Mussak EN, Kacker A. Surgical and medical management of midline ectopic thyroid. Otolaryngol Head Neck Surg. 2007;136(6):870-2.

Ibrahim NA, Fadeyibi IO. Ectopic thyroid: etiology, pathology and management. Hormones (Athens). 2011;10(4):261-9.

Ohnishi H, Sato H, Noda H, Inomata H, Sasaki N. Color Doppler ultrasonography: diagnosis of ectopic thyroid gland in patients with congenital hypothyroidism caused by thyroid dysgenesis. J Clin Endocrinol Metab. 2003;88(11):5145-9.

Weber AL, Randolph G, Aksoy FG. The thyroid and parathyroid glands. CT and MR imaging and correlation with pathology and clinical findings. Radiol Clin North Am. 2000;38(5):1105-29.

Altay C, Erdoğan N, Karasu S, Uluç E, Sarsılmaz A, Mete B, Oyar O. CT and MRI findings of developmental abnormalities and ectopia varieties of the thyroid gland. Diagn Interv Radiol. 2012 Jul;18(4):335-43.

Prado H, Prado A, Castillo B. Lateral ectopic thyroid: a case diagnosed preoperatively. Ear Nose Throat J. 2012;91(4):14-8.

J.G. Batsakis, A.K. El-Naggar, M.A. Luna. Thyroid gland ectopias Ann. Otol. Rhinol. Laryngol. 1996;105(12):996-1000.

Pelizzo MR, Torresan F, Grassetto G, Briani G, Marzola MC, Rubello D. Imaging identifies submandibular ectopic thyroid tissue. Clin Nucl Med. 2011;36(8):728-30.

Lingam RKFNM, Nigar E, Kalan A. Otorhinolaryngologist, 2011;3(3):118-20.

Mysorekar VV, Dandekar CP, Sreevathsa MR. Ectopic thyroid tissue in the parotid salivary gland. Singapore Med J. 2004;45(9):437-8.

A. Sahbaz, N. Aksakal, B. Ozcinar, F. Onuray, K. Caglayan, Y. Erbil. The “forgotten” goiter after total thyroidectomy. Int. J. Surg. Case Rep. 2013;4(3):269-71.

Shah BC, Ravichand CS, Juluri S, Agarwal A, Pramesh CS, Mistry RC. Ectopic thyroid cancer. Ann Thorac Cardiovasc Surg. 2007;13(2):122-4.

Vázquez OR, Silva F, Acosta-Pumarejo E, Marín ML. Ectopic Papillary Thyroid Cancer with Distant Metastasis. Case Rep Endocrinol. 2018;2018:8956712.

Toso A, Colombani F, Averono G, Aluffi P, Pia F. Lingual thyroid causing dysphagia and dyspnoea. Case reports and review of the literature. Acta Otorhinolaryngol Ital. 2009;29(4):213-7.

Kwak JY, Han KH, Yoon JH, Moon HJ, Son EJ, Park SH, et al. Thyroid imaging reporting and data system for US features of nodules: a step in establishing better stratification of cancer risk. Radiology. 2011;260(3):892-9.

Frates MC, Benson CB, Doubilet PM, Kunreuther E, Contreras M, Cibas ES, Orcutt J, et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab. 2006;91(9):3411-7.

Neinas FW, Gorman CA, Devine KD, Woolner LB. Lingual thyroid. Clinical characteristics of 15 cases. Ann Intern Med. 1973;79(2):205-10.

Alderson DJ, Lannigan FJ. Lingual thyroid presenting after previous thyroglossal cyst excision. J Laryngol Otol. 1994;108(4):341-3.