Bacteriological profile with antibiotic sensitivity pattern of burn wound infections in a peripheral tertiary care hospital
DOI:
https://doi.org/10.18203/2349-2902.isj20211307Keywords:
Burn, Wound infection, Bacteriological profile, Antibiotic susceptibilityAbstract
Background: India, has an estimated burn incidence of 6-7 million annually. Nearly 10% of these are life threatening and require hospitalization, and main cause of mortality and morbidity of these burn patients were wound infection and sepsis after 1st 24 hours. The present study was tried to determine specific pattern of burn wound infections, and antibiotic susceptibility of those isolates.
Methods: After matching inclusion and exclusion criteria, total 55 patients were taken for this institution based, prospective observational study. Wound swabs were collected on day 7 and cultured aerobically in MacConkey agar and 5% blood agar and antibiotic susceptibility testing was done on Muller Hinton agar using Kirby-Bauer disc diffusion method.
Results: Among study population 69.1% patients were female and majority (29.1%) of the patients belongs to age group from 21 to 30. It was found that 48 wound swabs were positive for microorganisms, of which Pseudomonas aeruginosa was most common isolated organism (23.6%), followed by Klebsiella pneumoniae (16.4%) and Staphylococcus aureus (14.5%). The most effective antibiotic found in this study was piperacillin/tazobactam, followed by imipenem/cilastatin.
Conclusions: It was seen that gram-negative organisms were more prevalent. Pseudomonas aeruginosa was the most common microorganism and piperacillin/tazobactam was most effective antibiotic.
References
Mestri SC. Role of Doctors in dowry deaths. JFMT. 1992;3(4).
Baker CC, Miller CL, Trunkey DD. Predicting fatal sepsis in burn patients. J Trauma. 1979;19:641-8.
Donati L, Scammazo F, Gervasoni M, Magliano A, Stankow B, et al. Infection andantibiotic therapy in 4000 burned patients in Milani Italy between 1976 and 1988. Burns. 1993;4:345-8.
Nagesha CN, Shenoy KJ, Chandrashekar MR. Study of burn sepsis with special reference to Pseudomonas aeruginosa. J Indian Med Assoc. 1996;94(6):230-3.
American Burn Association. National Burn Repository 2016 Report Chicago, IL. 2016. Available at: https://ameriburn.site-ym.com/general/custom.asp?page=NBRReports. Accessed on: 15 January 2021.
Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clin Microbiol Rev. 2006;19:403-34.
Bang RL, Sharma PN, Sanyal SC, Al Najjadah I. Septicaemia after burn injury: A comparative study. Burns. 2002;28:746-51.
Chakraborty S, Bisoi S, Chattopadhyay D, Mishra R, Bhattacharya N, Biswas B. A study on demographic and clinical profile of burn patients in a Apex institute of West Bengal. Indian J Public Health. 2010;54(1):27-9.
Jaiswal AK, Aggarwal H, Solanki P, Lubana PS, Mathur RK, Odiya S. Epidemiological and socio-cultural study of burn patients in M. Y hospital, Indore, India. Indian J Plast Surg. 2007;40(2):158-63.
Kaur H, Bhat J, Anvikar AR, Rao S, Gadge V. Bacterial profile of blood and burn wound infections in burn patients. Proceedings of National Symposium on Tribal Health. 2006;89-95.
Rajput A, Singh KP, Kumar V, Sexena R, Singh RK. Antibacterial resistance pattern of aerobic bacteria isolates from burn patients in tertiary care hospital. Biomed Res. 2008;19(1):1-4.
Ramakrishnan MK, Sankar J, Venkatraman J, Ramesh J. Infection in burn patients – experience in a tertiary care hospital. Burns. 2006;32:594-6.
Ekrami A, Kalantar E. Bacterial infections in burn patients at a burn hospital in Iran. Indian J Med Res. 2007;126:541-4.
Srinivasan S, Vartak AM, Patil A, Saldanha J. Bacteriology of the burn wound at the Bai Jerbai Wadia hospital for children, Mumbai, India – A 13 year study, Part I – Bacteriological profile. Indian J Plast Surg. 2009;42(2):213-8.
Bairy I, Shivananda PG. Aerobic bacterial flora of burn wound infection. Ind J Surg. 1997;59:215-8.
Nagoba BS, Deshmukh SR, Wadher BJ, Pathan AB. Bacteriological analysis of burn sepsis. Indian J Med Sci. 1999;53:216-9.
Lari AR, Alaghehbandan R. Nosocomial infections in an Iranian burn care center. Burns. 2000;26:737-40.
Ozumba UC, Jiburum BC. Bacteriology of burn wounds in Enugu, Nigeria. Burns. 2000;26:178-80.
Nasser S, Mabrouk A, Maher A. Colonization of burn wounds in Ains Shams University burn unit. Burns. 2003;29:229-33.
Kehinde AO, Ademola SA, Okesola AO, Oluwatosin OM, Bakare RA. Pattern of bacterial pathogens in burn wound infections in Ibadan, Nigeria. Ann Burns Fire Disasters. 2004;17(1):12-5.
Agnihotri N, Gupta V, Joshi RM. Aerobic bacterial isolates from burn wound infections and their antibiograms – a five year study. Burns. 2004;30:241-3.
Komolafe OO, James J, Kalongolera L, Makoka M. Bacteriology of burns at the Queen Elizabeth Central Hospital, Blantyre, Malawi. Burns. 2003;29:235-8.
Sengupta S, Kumar P, Ciraj AM, Shivananda PG. Acinetobacter baumanii –An emerging nosocomial pathogen in the burn unit Manipal, India. Burns. 2001;27:140-4.
Guggenheim M, Zbinden R, Handschin AE, Gohritz A, Altintas MA, Giovanoli P. Changes in bacterial isolates from burn wounds and their antibiograms: A 20 year study (1986-2005). Burns. 2009;35:553-60.
Mehta M, Dutta P, Gupta V. Bacterial isolates from burn wound infections and their antibiograms: A eight-year study. Indian J Plast Surg. 2007;40(1):25-8.
de Macedo JLS, Santos JB. Bacterial and fungal colonization of burn wounds. Mem Inst Oswaldo Cruz, Rio de Janeiro. 2005;100(5):535-9.
Rastegar Lari AR, Alaghehbandan R, Akhlaghi L. Burn wound infections and antimicrobial resistance in Tehran, Iran: an increasing problem. Ann Burn Fire Disasters. 2005;18(2):68-73.
Oncul O, Ulkur E, Acar A, Turhan V, Yeniz E, Karacaer Z, et al. Prospective analysis of nosocomial infections in a burn care unit, Turkey. Indian J Med Res. 2009;130:758-64.
Imran M, Faheem M, Aslam V, Hakeem A, Rehman I, Shah A. Wound infections and culture sensitivity pattern in paediatric burn patients. JPMI. 209;23(4):304-8.
