Two case reports of malignant melanoma rectum
Keywords:Malignant anorectal melanoma, Rare case, Abdomino-perineal resection, Adjuvant chemo-radiotherapy, Colostomy
Malignant melanoma of the rectum is an extremely rare disease. It typically presents in the fifth or sixth decade predominantly in female sex. The first symptoms are nonspecific such as bleeding, anal mass or pain. A timely diagnosis of melanoma is made even more difficult due to lack of obvious pigmentation and histologically amelanotic. Anorectal malignant melanoma spread along submucosal planes and are often beyond complete resection at the time of diagnosis. Prognosis is very poor. We present a rare case of malignant melanoma of rectum in a 21-year-old male, who was diagnosed at advanced stage, and a case of malignant melanoma in a 50-year-old male, who underwent abdominoperineal resection with permanent colostomy. Anorectal malignant melanoma is difficult to diagnose and prognosis is poor.
Roviello F, Cioppa T, Marrelli D, Nastri G, De Stefano A, Hako L, et al. Primary ano-rectal melanoma: considerations on a clinical case and review of the literature. Chir Ital. 2003:575-80.
Solaz Moreno E, Vallalta Morales M, Silla Búrdalo G, Cervera Miguel JI, Díaz Beveridge R, Rayón Martín JM. Primary melanoma of the rectum: an infrequent neoplasia with an atypical presentation. Clin Transl Oncol. 2005;7(4):171-3.
Singer M, Mutch MG. Anal melanoma. Clin Colon Rectal Surg. 2006;19:78-87.
Schaik VPM, Ernst MF, Meijer HA, Bosscha K. Melanoma of the rectum: a rare entity. World J Gastroenterol. 2008;14(10):1633-5.
Stefanou A, Nalamati SP. Anorectal melanoma. Clin Colon Rectal Surg. 2011;24(3):171-6.
Liptrot S, Semeraro D, Ferguson A, Hurst N. Malignant melanoma of the rectum: a case report. J Med Case Rep. 2009;3:9318.
Morson BC, Volkstädt H. Malignant melanoma of the anal canal. J Clin Pathol. 1963 Mar;16(2):126-32.
Row D, Weiser MR. Anorectal melanoma. Clin Colon Rectal Surg. 2009;22(2):120-6.
Reid A, Dettrick A, Oakenful C, Lambrianides A. Primary rectal melanoma. J Surg Case Rep. 2011;2011(11):2.
Ballo MT, Gershenwald JE, Zagars GK, Lee JE, Mansfield PF, Strom EA, et al. Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma. J Clin Oncol. 2002;20(23):4555-8.
Carcoforo P, Raiji MT, Palini GM, Pedriali M, Maestroni U, Soliani G, et al. Primary anorectal melanoma: an update. J Cancer. 2012;3:449-53.
Kim KW, Ha HK, Kim AY, Kim TK, Kim JS, Yu CS, et al. Primary malignant melanoma of the rectum: CT findings in eight patients. Radiology. 2004;232(1):181-6.
Matsuoka H, Nakamura A, Iwamoto K, Sugiyama M, Hachiya J, Atomi Y, Masaki T. Anorectal malignant melanoma: preoperative usefulness of magnetic resonance imaging. J Gastroenterol. 2005;40(8):836-42.