Primary cutaneous mucinous carcinoma of axilla: a case report with review of literature

Authors

  • Sanjivi Kamat Department of General Surgery, Goa Medical College and Hospital, Bambolim, Panaji, Goa, India http://orcid.org/0000-0002-0127-6311
  • Manohar Malawad Department of General Surgery, Goa Medical College and Hospital, Bambolim, Panaji, Goa, India
  • Rajesh Patil Department of General Surgery, Goa Medical College and Hospital, Bambolim, Panaji, Goa, India

DOI:

https://doi.org/10.18203/2349-2902.isj20210946

Keywords:

Mucinous carcinoma of skin, Primary cutaneous mucinous carcinoma, Axilla

Abstract

Primary cutaneous mucinous carcinoma is a low grade tumour of the sweat gland rarely occurring in middle aged men, more commonly in the sixth decade. When seen in a younger age group, the tumour tends to be more aggressive with potential for metastasis. Clinical presentation is usually a hard nodular well defined painless lesion confined to skin and subcutaneous tissue, commonly seen in head and neck region. Histopathological examination of the specimen shows cells with myxoid and mucinous material, confirmed by immunohistochemistry showing positive for estrogens and progesterone receptor and cytokeratin 7, is diagnostic. Surgery is the treatment of choice, wide local excision with margin of 1 cm as this tumor is resistant to radiotherapy and chemotherapy. Its tendency for late recurrences and rare metastasis, adds to the good prognosis. With rare chances of distant metastasis, prognosis remains good but local recurrences are not uncommon after excision.

Author Biography

Sanjivi Kamat, Department of General Surgery, Goa Medical College and Hospital, Bambolim, Panaji, Goa, India

Department of General Surgery, Goa Medical College

Department of Plastic Surgery and Burns, Goa Medical College

References

Lennox B, Pearse AG, Richards HG. Mucin-secreting tumours of the skin with special reference to the so-called mixed-salivary tumour of the skin and its relation to hidradenoma. J Pathol Bacteriol. 1952;64(4):865-80.

Papalas JA, Proia AD. Primary mucinous carcinoma of the eyelid: a clinicopathologic and immunohistochemical study of 4 cases and an update on recurrence rates. Arch Ophthalmol. 2010; 128(9):1160-5.

Breiting L, Christensen L, Dahlstrøm K, Breiting V, Winther JF. Primary mucinous carcinoma of the skin: a population-based study. Int J Dermatol. 2008;47(3):242-5.

Martinez SR, Young SE. Primary mucinous carcinoma of the skin: a review. J Oncol. 2005; 2(2):40-5.

Kamalpour L, Brindise RT, Nodzenski M, Bach DQ, Veledar E, Alam M. Primary cutaneous mucinous carcinoma: a systematic review and meta-analysis of outcomes after surgery. JAMA Dermatol. 2014;150(4):380-4.

Scilletta A, Soma PF, Grasso G, Scilletta R, Pompili G, Tarico MS, Perrotta RE. Primary cutaneous mucinous carcinoma of the cheek. Case report. G Chir. 2011;32(6-7):323-5.

Downloads

Published

2021-02-25

Issue

Section

Case Reports