Published: 2021-02-25

Duodenal adenocarcinoma: a rare cause of intestinal obstruction in young adult

Parth Parmar, Shadan Ali, Romesh Lal, Saurabh Borgharia, Manoj Andley, Gyan Saurabh


Primary adenocarcinoma of duodenum is a very rare and aggressive malignancy, found in middle or elderly age group and usually arising in the second portion of the duodenum, followed by third or fourth. Cancers of the first portion of the duodenum, especially the duodenal bulb are extremely rare. The causative factors for duodenal adenocarcinoma are dietary factors, ingestion of alcohol, coffee and use of tobacco. It may occur from duodenal polyps present in familial polyposis or may be associated. In young age it is associated with polyposis syndromes or with Crohn’s disease affecting small bowel. Very few reports discuss the diagnosis and treatment of such malignancy and very few cases have been reported in young age less than 30years. We are reporting a case of 22 years old gentleman who presented to us with history of recurrent abdominal pain and vomiting. After evaluation it was diagnosed as adenocarcinoma of third and fourth part of duodenum without any associated syndromes or inflammatory bowel diseases and was managed by surgical resection and chemotherapy.


Duodenal adenocarcinoma, Young adult, Intestinal obstruction

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