High-intensity focused ultrasound for the treatment of hepatic echinococcosis

Zhenzhen Chen; Haitham Salameen; Jianping Gong; Xuegang Wen

doi:10.18203/2349-2902.isj20211310

Authors

Zhenzhen Chen Department of Hepatobiliary/Cardiothoracic Surgery, Zhongxian Hospital People’s Hospital of Chongqing, China
Haitham Salameen Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Jianping Gong Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Xuegang Wen Department of Hepatobiliary/Cardiothoracic Surgery, Zhongxian Hospital People’s Hospital of Chongqing, China

DOI:

https://doi.org/10.18203/2349-2902.isj20211310

Keywords:

Hepatic echinococcosis, Combination therapy

Abstract

Objective of the study was to investigate the safety and effectiveness of high-intensity focused ultrasound (HIFU) to treat hepatic echinococcosis (HE). Eight HE patients treated between 2008 and 2010 were evaluated for the effectiveness of HIFU treatment; the occurrence of complications such as post treatment pain, fever, and skin burns; prognosis; and recurrence. Clinical and imaging evaluation of disease improved after treatment in all eight patients. Postoperatively, all patients experienced changes in liver function that returned to normal within 5 days. Three patients experienced low-grade fever that resolved in 6 days. Six patients complained of right upper quadrant pain that resolved in 7 days. Three patients experienced minor swelling of the skin. No unexpected complications were noted. HIFU was safe and effective for treating HE. It is non-invasive and caused no severe postoperative complications.

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References

Bhutani N, Kajal P. Hepatic echinococcosis: a review. Ann Med Surg 201;36:99-105.

Jiang C. Today's regional distribution of echinococcosis in China. Chin Med J (Engl). 2002;115(8):1244-7.

Ahmed Z, Chhabra S, Massey A, Vij V, Yadav R, Bugalia R, et al. Primary hydatid cyst of pancreas: Case report and review of literature. Int J Surg Case Rep. 2016;27:74-7.

Ammann RW, Eckert J. Cestodes. Echinococcus. Gastroenterol Clin North Am. 1996;25(3):655-89.

Brunetti E, White AC. Cestode infestations: hydatid disease and cysticercosis. Infect Dis Clin North Am. 2012;26(2):421-35.

Langer JC, Rose DB, Keystone JS, Taylor BR, Langer B. Diagnosis and management of hydatid disease of the liver. A 15-year North American experience. Ann Surg. 1984;199(4):412-7.

Karadas S, Cumhur DA, Bilge G, Mehmet B, Mustafa K. A case of Budd-Chiari syndrome associated with alveolar echinococcosis. J Pak Med Assoc. 2014;64(4):465-7.

Chen X, Chen X, Lu X, Feng X, Wen H. The production and comparative evaluation of native and recombinant antigens for the fast serodiagnosis of cystic echinococcosis with dot immunogold filtration assay. Parasite Immunol. 2015;37(1):10-5.

Knapp J, Sako Y, Grenouillet F, Bresson-Hadni S, Richou C, Gbaguidi-Haore H, et al. Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France. Parasite. 2014;21:34.

Şakalar Ç, Kuk S, Erensoy A, Dağli AF, Özercan İH, Çetınkaya Ü, Yazar S. Molecular discrimination of Echinococcus granulosus and Echinococcus multilocularis by sequencing and a new PCR-RFLP method with the potential use for other Echinococcus species. Turk J Med Sci. 2014;44(5):741-8.

Wang WT, Yang C, Yan LN. New concept and strategy of radical surgical treatment of hepatic echinococcosis.Zhonghua Yi Xue Za Zhi. 2018;98(38):3049-51.

Avdaj A, Namani S. Surgical treatment of hepatic echinococcosis in Prizren (Kosovo). Ann Med Surg (Lond). 2014;3(4):130-3.

Buttenschoen K, Carli Buttenschoen DC, Gruener B. Long-term experience on surgical treatment of alveolar echinococcosis. Langenbeck's Arch Surg. 2009;394(4):689-98.

Du C, Liu Z, Yang X, Yan L, Li B, Wen T, et al. Hepatectomy for patients with alveolar echinococcosis: long-term follow-up observations of 144 cases. Int J Surg. 2016;35:147-52.

Tamarozzi F, Vuitton L, Brunetti E, Vuitton DA, Koch S. Non-surgical and non-chemical attempts to treat echinococcosis: do they work? Parasite. 2014;21:75.

Vuitton DA, Azizi A, Richou C, Vuitton L, Blagosklonov O, Delabrousse E, et al. Current interventional strategy for the treatment of hepatic alveolar echinococcosis. Expert Rev Anti Infect Ther. 2016:14(12)1-3.

Koch S, Bresson-Hadni S, Miguet JP, Crumbach JP, Gillet M, Mantion GA, et al. Experience of liver transplantation for incurable alveolar echinococcosis: a 45-case European collaborative report. Transplantation. 2003;75(6):856-63.

Gollackner B, Längle F, Auer H, Maier A, Mittlböck M, Agstner I, et al. Radical surgical therapy of abdominal cystic hydatid disease: factors of recurrence. World J Surg. 2000;24(6):712-6.

She WH, Cheung TT, Jenkins CR, Irwin MG. Clinical applications of high-intensity focused ultrasound. HK Med J. 2016;22(4):382-92.

Vaezy S, Zderic V. Hemorrhage control using high intensity focused ultrasound. Int J Hyperthermia. 2007;23(2):203-11.

Sarkar M, Pathania R, Jhobta A, Thakur BR, Chopra R. Cystic pulmonary hydatidosis. Lung India. 2016;33(2):179-91.