Verrucous carcinoma of foot: a diagnostic enigma

Sai Suraj Kotera; Manjunath K.; Rajagopalan S.

doi:10.18203/2349-2902.isj20160259

Authors

Sai Suraj Kotera Department of General Surgery, Rajarajeswari medical college and hospital, Bangalore, India
Manjunath K. Department of General Surgery, Rajarajeswari medical college and hospital, Bangalore, India
Rajagopalan S. Department of General Surgery, Rajarajeswari medical college and hospital, Bangalore, India

DOI:

https://doi.org/10.18203/2349-2902.isj20160259

Keywords:

Verrucous carcinoma, Dermal malignancy, Wide excision

Abstract

We present two cases of Verrucous Carcinoma (VC) of the foot in middle aged men. This is a rare locally invasive, well differentiated and low grade squamous cell carcinoma (SCC) with Human Papilloma Virus as a possible causative agent. It follows a chronic course and mimics various skin lesions which lead to delay in diagnosis by up to 15 years. The diagnosis is made histologically and treatment is wide local excision. Though at 1 year follow up showed no signs of recurrence. Due to confusion of diagnosis in the early stage, there will be delayed diagnosis. So early pathological diagnosis and intervention are key determinants for better prognosis.

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References

Ackerman LV. Verrucous carcinoma of the oral cavity. Surgery. 1948;23(4):670-78.

Santoro A, Pannone G, Contaldo M. A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report. Journal of Skin Cancer. 2011. doi:10.1155/2011/370605.

Shroyer KR, Greer RO, Fankhouser CA, McGuirt WF, Marshall R. Detection of human papillomavirus DNA in oral verrucous carcinoma by polymerase chain reaction. Modern Pathology. 1993;6(6);669-72.

Garven TC, Thelmo WL, Victor J, Pertschuk L. Verrucous carcinoma of the leg positive for human papillomavirus DNA 11 and 18: a case report. Hum Pathol. 1991;22:1170-3.

Suen K, Wijeratne S, Patrikios J. An unusual case of bilateral verrucous carcinoma of the foot (epithelioma cunicilatum). Journal of Surgical Case Reports. 2012;2012(12): rjs020.

Kathuria S, Rieker J, Jablokow VR, Van Den Broek H. Plantar verrucous carcinoma (epithelioma cuniculatum): case report with review of literature. J Surg Oncol. 1986;31:71-5.

Lesic A, Nikolic M, Sopta J, Starcevic B, Atkinson HD. Verrucous carcinoma of the foot: a case report. J Orthop Surg. (Hong Kong). 2008;16(2):251-3.

Miller SB, Brandes BA, Mahmarian RR, Durham JR. Verrucous carcinoma of the foot: a review and report of two cases. J Foot Ankle Surg. 2001;40:225-31.

Wright PK, Vidyadharan R, Jose RM, Rao GS. Plantar verrucous carcinoma continues to be mistaken for verruca vulgaris. Plast Reconstr Surg. 2004;113:1101-3.

Smith PJ, Hylinski JH, Axe S. Verrucous carcinoma: epithelioma cuniculatum plantare. J Foot Surg. 1992;31:324-8.

Dogan G, Oram Y, Hazneci E, Ozen S, Karincaoglu Y, Ciralik H. Three cases of verrucous carcinoma. Australas J Dermatol. 1998;39:251-4.

Tharp ME II, Shidnia H. Radiotherapy in the treatment of verrucous carcinoma of the head and neck. Laryngoscope. 1995;105(4):391-96.