DOI: http://dx.doi.org/10.18203/2349-2902.isj20204668

Role of streptokinase in management of retained hemothorax: a multicentric study

Ankur Varma, Ravikant Narain, Parag Deshmukh, Himmat Rathore, S. G. S. Datta, Aditi V. Varma, Pawan Sharma, Jebin Joseph

Abstract


Background: Enzymatic debridement of the pleural cavity for retained haemothorax is a frequently overlooked option.

Methods: A retrospective, multicentre study was carried out using intrapleural streptokinase was carried out in 15 patients with retained or clotted haemothorax.

Results: Thirteen of fifteen patients (86%) with retained pleural collections underwent successful enzymatic debridement and tube drainage with streptokinase injections in our study. The average increase in chest tube output following streptokinase injections was 160%. No significant adverse reactions occurred. Two patients required thoracotomy when streptokinase therapy failed. No deaths were reported in the study.

Conclusions: Intrapleural streptokinase is a safe, effective means of removing retained proteinaceous collections in the pleural space. It is a useful adjunct to chest tube drainage and may obviate the need for more invasive procedures.


Keywords


Clotted haemothorax, Streptokinase, Fibrinolytic drug

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References


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