Primary anal malignant melanoma: a case report

Authors

  • Bharti Saraswat Department of General Surgery, Dr. SN Medical College, Jodhpur, Rajasthan
  • Richa Purohit Department of General Surgery, Dr. SN Medical College, Jodhpur, Rajasthan
  • Anuj Singh Department of General Surgery, Dr. SN Medical College, Jodhpur, Rajasthan
  • Ramratan Yadav Department of General Surgery, Dr. SN Medical College, Jodhpur, Rajasthan

Keywords:

Malignant melanoma, Anal canal, Extracutaneous

Abstract

Primary anal malignant melanoma is an uncommon and aggressive disease. In many cases, the disease is undetected or mistaken for a benign polyp or haemorrhoids until it reaches an advanced stage. Extracutaneous melanomas require special consideration due to their late diagnosis and consequently poor prognosis. Extracutaneous melanomas are considered to be biologically more aggressive than their cutaneous counterparts. Surgical excision remains the cornerstone of therapy. This case is reported because of the rarity of the disease in anal canal found in an 80 year old female who was managed with wide local excision of the growth.

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References

Zhang S, Gao F, Wan D. Effect of misdiagnosis on the prognosis of anorectal malignant melanoma. J cancer Res Clin Oncol. 2010;136:1401-5.

Moore R. Recurrent melanosis of the rectum, after previous removal from the verge of the anus, in a man aged sixty-five. Lancet. 1857;1:290.

Thibault C, Sagar P, Nivatvongs S, Ilstrup DM, Wolff BG. Anorectal melanoma: an incurable disease? Dis Colon Rectum. 1997;40(6):661-8.

Chang AE, Karnell LH, Menck HR. The National cancer data base report on cutaneous and noncutaneous melanoma: a summary of 84836 cases from the past decade. Am Coll Surg Commis Cancer Am Cancer Soc Cancer. 1998;83(8):1664-78.

Klas JV, Rothenberger DA, Wong WD, Madoff RD. Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes. Cancer. 1999;85(8):1686-93.

Brady MS, Kavolius JP, Quan SHQ. Anorectal melanoma: a 64-year experience at memorial Sloan-Kettering cancer center. Dis Colon Rectum. 1995;38(2):146-51.

Slingluff CL, Seigler HF. Anorectal melanoma: clinical characteristics and the role of abdominoperineal resection. Ann Plast Surg. 1992;28(1):85-8.

Heyn J, Placzek M, Ozimek A, Baumgaertner AK, Siebeck M, Volkenandt M. Malignant melanoma of the anal region. Clin Experiment Dermatol. 2007;32(5):603-7.

Konstadoulakis MM, Ricaniadis N, Walsh D, Karakousis CP. Malignant melanoma of the anorectal region. J Surg Oncol. 1995;58(2):118-20.

Roumen RMH. Anorectal melanoma in the Netherlands: a report of 63 patients. Eur J Surg Oncol. 1996;22(6):598-601,

Cooper PH, Mills SE, Allen MS. Malignant melanoma of the anus. Report of 12 patients and analysis of 255 additional cases. Dis Colon Rectum. 1982;25(7):693-703.

Felz MW, Winburn GB, Kallab AM, Lee JR. Anal melanoma: an aggressive malignancy masquerading as haemorrhoids. South Med J. 2001;94:880-5.

Morsan BC, Volkstadt H. Malignant melanoma of the anal canal. J Clin Pathol. 1963;16:126-32.

Chute DJ, Cousar JB, Mills SE. Anorectal malignant melanoma: morphologic and immunohistochemical features. Am J Clin Pathol. 2006;126:93-100.

Zhuo HT, Zhuo ZX, Zhang HZ, Bi JJ, Zhao P. Wide local excision could be considered as the initial treatment of primary anorectal malignant melanoma. Chin Med J (Engl). 2010;123:585-8.

Iddings DM, Fleisig AJ, Chen SL, Faries MB, Morton DL. Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients? Ann Surg Oncol. 2010;17:40-4.

Bullard KM, Tuttle TM, Rothenberger DA, Madoff RD, Baxter NN, Finne CO, et al. Surgical therapy for anorectal melanoma. J Am Coll Surg. 2003;196:206-11.

Tien HY, McMasters KM, Edwards MJ, Chao C. Sentinel lymph node metastasis in anal melanoma: a case report. Int J Gastrointest Cancer. 2002;32:53-6.

Thompson LW, Brinckerhoff L, Slingluff CL. Vaccination for melanoma. Curr Oncol Rep. 2000;2:292-9.

Ballo MT, Gershenwald JE, Zagars GK, Lee JE, Mansfield PF, Strom EA, et al. Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma. J Clin Oncol. 2002;20:4555-8.

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Published

2016-12-13

How to Cite

Saraswat, B., Purohit, R., Singh, A., & Yadav, R. (2016). Primary anal malignant melanoma: a case report. International Surgery Journal, 2(2), 304–307. Retrieved from https://www.ijsurgery.com/index.php/isj/article/view/600

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Section

Case Reports