DOI: http://dx.doi.org/10.18203/2349-2902.isj20202416

A retrospective observational study of clinical profile, diagnosis, management and outcome of abdominal tuberculosis in 30 patients

Mukesh Pancholi, Mahendra Kumar Meena, Praveen Sharma, Devendra Chaudhary

Abstract


Background: Abdominal tuberculosis is found worldwide although prevalence rates are still highest in the developing countries. The sites of involvement of abdominal tuberculosis are peritoneum, lymph nodes, intestine and solid viscera. The objectives of this study were to describe the clinical profile of patients with abdominal tuberculosis, to review the use of diagnostic modalities, both non-invasive and invasive and to study the outcome of management of abdominal tuberculosis.

Methods: This is an observational retrospective study of 30 patients with diagnosis of abdominal tuberculosis treated at university linked teaching hospital of South Gujarat from August 2015 to November 2017.

Results: In our study, disease was found almost equally prevalent in both rural and urban areas affecting mostly lower socio-economical class. The mean age was 34 years (range from 13 to 62); male and female ratio was 2.33:1; the mean hospital stay was 09 days (range from 5 to 48 days). Abdominal pain was present in almost all cases, having chronic pain in 21 patients and acute in 9 patients. There were 05 (16.7%) patients found to be HIV positive in this study. There was mortality of 02 patients post operatively due to sepsis in those patients operated in emergency with peritonitis.

Conclusions: Abdominal tuberculosis is prevalent in lower socioeconomic class patients and affects younger male patients more commonly. Most commonly intestinal and mesenteric disease presented with chronic abdominal pain and constitutional symptoms of tuberculosis.


Keywords


Abdominal tuberculosis, Anti Koch’s therapy, Intestinal stricture

Full Text:

PDF

References


Singh A, Sahu MK, Panigrahi M, Behera MK, Singh KU, Kar C, et al. Abdominal tuberculosis in Indians: Still very pertinent; J Clin Tuberc Other Mycobact Dis. 2019;15:100097.

Horvath KD. Whelan RL. Intestinal tuberculosis: return of an old disease. Am J Gastroenterol 1998;93:692-6.

Nayagam JS, Mullender C, Cosgrove C, Poullis A. Abdominal tuberculosis: diagnosis and demographics, a 10-year retrospective review from a single centre. World J Clin Cases. 2016;4(8):207-12.

Bhansali SK. Abdominal Tuberculosis. Experiences with 300 cases. Am J Gastroenterol. 1977;67:324-37.

Tandon RK, Bansal R, Kapur BML, Shriniwas. A study of malabsorption in intestinal tuberculosis: stagnant loop syndrome. Am J Clin Nutr. 1980;33(2):244-50.

Noomene R, Ouaka A, Jouini R, Cherif A. What Remains to Surgeons in the Management of Abdominal Tuberculosis? A 10 Years’ Experience in an Endemic Area; Indian J Tuberc. 2017;64(3):167-72.

Mandavdhare HS, Singh H, Dutta U, Sharma V. A real‐world experience with 6 months of antitubercular therapy in abdominal tuberculosis. J Gastroenterol Hepatol. 2019;3:201-5.

Khan R, Abid S, Jafri W, Abbas Z. Diagnostic dilemma of abdominal tuberculosis in non-HIV patients: an ongoing challenge for physicians. World J Gastroenterol. 2006;39:6371-5.

Urabinahatti KA, Singh AK, Nayak A, Gupta R. Abdominal tuberculosis: an epidemiological profile and management of 40 cases in a tertiary set up. Int Surg J. 2016;3:1502-8.

Aggarwal P, Kedia S, Sharma R, Bopanna S, Madhusudhan KS, Yadav DP. et al. Tubercular intestinal strictures show a poor response to anti-tuberculous therapy. Dig Dis Sci. 2017;62:2847-56.

Balasubramanian R, Nagarajan M, Balambal R, Tripathy SP, Sundararaman R, Venkatesan P, et al. Randomized controlled clinical trial of short course chemotherapy in abdominal tuberculosis: a five-year report. Int J Tuberculosis Lung Dis. 1997;1(1):44-51.

Mukhopadhyay A, Dey R, Bhattacharya U. Abdominal tuberculosis with an acute abdomen: our clinical experience. J Clin Diagnos Res. 2014;8(7):NC07-9.

Miah AR, Sharma YR, Rahman MT, Raihan A. Clinicopathological Profile of Patients with Abdominal Tuberculosis; J Nepal Health Res Counc. 2011;9(2):169-75.