Prevalence of surgical site infections and their sensitivity patterns in elective abdominal surgeries in King George Hospital, Visakhapatnam

Pratha Anantha Ramani, Simhadri Uday Kiran, Murali Manohar Deevi, Ginni Vijay Sainath Reddy, Ginjupalli Saichand, Sivaram Shashank Yeeli, Potireddy Yaswanth Reddy


Background: Surgical site infections are one of the most common complications in the postoperative period leading to increased morbidity, prolonged hospital stay and reduced quality of life. The present study aims to identify the incidence of surgical site infection (SSI), risk factors, causative organisms, and their sensitivity patterns in patients who have undergone elective abdominal surgeries.

Methods: A prospective study containing 200 patients who have undergone elective abdominal surgeries from May 2018 to January 2020 were evaluated. A thorough history was taken in all the patients. A detailed clinical examination and routine investigations were done. Parameters such as body mass index (BMI), diabetic status, type of surgery, wound grading, culture, and sensitivity patterns were considered. The patients underwent treatment based on their investigatory reports.

Results: In the present study, 54 patients developed surgical site infection, and among them, 22 are diabetics. Only ten patients with normal BMI developed SSI, whereas the other 44 patients who developed SSI had abnormal BMI. The incidence of SSI was higher in clean-contaminated surgeries comprising up to 89% of cases. Staphylococcus aureus was the most commonly isolated organism, and cefoperazone plus sulbactam was the most sensitive on antibiogram.

Conclusions: The surgical site infections are on rising trend due to the emergence of antibiotic-resistant microorganisms. Treatment of the underlying risk factors, regular wound dressings, and antibiotics, according to sensitivity patterns, are the mainstay.



Surgical site infections, Elective abdominal surgeries, Diabetes, BMI, Antibiotics, Sensitivity

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Setty NK, Nagaraja M, Nagappa D, Naik L, Giriyaiah C, Gowda N. A study on Surgical Site Infections (SSI) and associated factors in a government tertiary care teaching hospital in Mysore, Karnataka. Int J Med Public Health, 2014;4(2):171.

Mukagendaneza, MJ, Munyaneza E, Muhawenayo, E, Nyirasebura D, Abahuje E, Nyirigira J, et al. Incidence, root causes, and outcomes of surgical site infections in a tertiary care hospital in Rwanda: a prospective observational cohort study. Patient Saf Surg. 2019;13:10.

Curcio D, Cane A, Fernández F, Correa J. Surgical site infection in elective clean and clean-contaminated surgeries in developing countries. Int J Infect Dis. 2019;80:34-45.

Awoke N, Arba A, Girma A. Magnitude of surgical site infection and its associated factors among patients who underwent a surgical procedure at Wolaita Sodo University Teaching and Referral Hospital, South Ethiopia. PLOS One. 2019;14(12):e0226140.

Purba AKR, Setiawan D, Bathoorn E, Postma MJ, Dik JWH, Friedrich AW. Prevention of Surgical Site Infections: A Systematic Review of Cost Analyses in the Use of Prophylactic Antibiotics. Frontiers in Pharmacol. 2018;9:776.

Kumar TVR, Goud KA. A study of surgical site infections in a general practice hospital. Int Surg J. 2019;6(11):4043-7.

Watanabe A, Kohnoe S, Shimabukuro R, Yamanaka T, Iso Y, Baba H, et al. Risk factors associated with surgical site infection in upper and lower gastrointestinal surgery. Surg Today. 2008;38:404- 12.

Azoury S, Farrow N, Hu Q, Soares K, Hicks C, Azar F, et al. Postoperative abdominal wound infection epidemiology, risk factors, identification, and management. Chron Wound Care Manage Res. 2015;2:137-48.

Astagneau P, Rioux C, Golliot F, Brücker G. Morbidity and mortality associated with surgical site infections: results from the 1997-1999 INCISO surveillance. J Hospital Infect. 2001;48:267-74.

Alkaaki A, Al-Radi O, Khoja A, Alnawawi A, Maghrabi A, Altaf A, et al. Surgical site infection following abdominal surgery: a prospective cohort study. Can J Surg. 2019;62(2):162-8.