Published: 2020-05-26

A prospective study to determine the accuracy of triple test score in breast lump

Vinod Kumar Pandey, Sarvesh Yadav, Shirish Mishra, Rohit Singh, Ankur Dutt Tripathi


Background: Breast cancer is the most common cancer in women worldwide. The commonest mode of presentation of diseases of the breast is lump. It is the most common site-specific cancer in women. Triple test score which includes clinical breast examination, mammogram, FNAC score. A simple non-invasive but reliable test can make a huge difference in management between benign and malignant lumps. Aims and objectives of the study were to differentiate between benign and malignant lesions based on TTS and correlated the accuracy of triple test score with histopathology report, and plan the management accordingly.

Methods: A prospective study was carried out in which TTS was calculated by summation of individuals’ scores of all three components and compare with histopathology report.

Results: In present study of 74 patients (age group of 30 to 65 years), based on TT score 52 benign, 12 malignant, and 10 suspicious (neither benign nor malignant). But the final histopathological result showed 59 as benign and 15 as malignant, which is in concordant with TTS, which shows the accuracy of up to 100%. Out of 10 (suspicious) which were dis-concordant, 7 are benign and 3 are malignant on histopathology.

Conclusions: By use of the triple test score and its interpretation, definitive treatment can be initiated, which would reduce the need for unnecessary biopsy and its ability to predict benign lump, can avoid major surgery.


Breast lump, FNAC, Mammogram, Triple test score

Full Text:



Baum M. Carcinoma of breast. In: Recent advances in surgery, London. Churchill Livingstone; 1984: 241-258.

Kirby IB, Samuel WB. The breast. In: Schwartz’s Principles of Surgery. McGraw Hill; 2005:475-77.

Klein S. Evaluation of palpable breast masses. Am Fam Phys. 2005;719:1731-8.

Thomas MJ, Fitzharris BM, Redding HW. Clinical examination, xeromammography and fine-needle aspiration cytology in diagnosis of breast tumors. BMJ. 1978;2:1139-41.

Yelland A, Graham DM, Trott AP. Diagnosing breast carcinoma in young women. BMJ. 1991;302:618-20.

Karla K, Rebecca S, Britt ML. Evaluation of abnormal mammography results and palpable breast abnormalities. Ann intern Med. 2003;139:274-84.

Gaikwad SR, Talpallikar MC, Tapadia JK, Gajakos AS. Diagnostic evaluation of triple test in detection of breast lesions. Int Surg J. 2019;6:586-9.

Morris A, Pommier RF, Schnidt WA, Shih RL, Alexander PW, Vetto JT. Accurate evaluation of palpable breast masses by triple test score. Arch Surg. 1998;133:930-4.

Ghimire B, Khan MI, Bibhusal T, Singh Y, Sayami P. Accuracy of triple test score in the diagnosis of palpable breast lump. J Nepal Med Assoc. 2008;47(172):189-92.

Katti P, Choudhary A, Sreeramulu PN, Agrawal V. Evaluation of triple test score in palpable breast lump. Sch J App Med Sci. 2016;4:1278-82.