A comparative study on treatment of keloid with triamcinolone versus 5-fluorouracil and triamcinolone


  • C. V. Praveen Kumar Reddy Department of Plastic surgery, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
  • Surekha A. Department of Dermatology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India




Keloid, Triamcinolone, 5-Fluorouracil


Background: The study was done to assess and compare the treatment of keloids with intralesional triamcinolone and combination of 5-fluorouracil and triamcinolone. Despite various options available, there is no universally accepted treatment for keloids. Our objective was to compare two regimens and establish superiority in terms of objective and subjective outcomes

Methods: A randomized parallel group study conducted in the Department of Plastic Surgery from January 2017 to June 2019. A total of 80 patients were taken with 40 each group.

Results: Though there was improvement in both regimens, this was more significant with combination regimen especially with vascularity, pliability, decrease in height and faster relief of symptoms like pain and itching.

Conclusions: Both were effective in treatment of keloids; triamcinolone alone was having relapse rate and combination therapy was more effective with faster results and few side effects.



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Original Research Articles