Radiation induced vasculitis of iliac veins: presentation of a case and therapeutic dilemmas
Keywords:Radiation, Vasculitis, Iliac veins, Phlebitis
A case of radiation-induced venous stenosis (phlebitis) after pelvic irradiation in a patient with prostate cancer is reported. Progressive swelling of both lower limbs developed due to bilateral external iliac vein stenosis. Conservative treatment with new oral anticoagulants and elastic stockings was conducted with clinical improvement of symptoms. Serial duplex scanning with trimestral frequency reveals no other progression of stenosis and the patient is well 2 years after diagnosis. Lack of data in the current literature makes management of this disease problematic.
Himmel PD, Hassett JM. Radiation-induced chronic arterial injury. Semin Surg Oncol. 1986;2(4):225-47.
Zhou W, Bush RL, Lin PH, Lumsden AB. Radiation-associated venous stenosis: endovascular treatment options. J Vasc Surg. 2004;40:179-82.
Elias HK, Jan MF, Allaqaband SQ. Role of endovascular stenting in radiation-induced stenosis of lower extremity veins. Catheter Cardiovasc Interv. 2015;86:312-5.
Girinsky T. Effects of ionizing radiation on the blood vessel wall. J Mal Vasc. 2000;25:321-4.