Enveloped double purse-string versus conventional pancreatico-gastrostomy during Whipple procedure: comparative study at Sohag university onco-surgery program

Authors

  • Ashraf M. El-Badry Department of General Surgery, Sohag University Hospital, Faculty of Medicine, Sohag University, Sohag, Egypt
  • Alaa A. Redwan Department of General Surgery, Sohag University Hospital, Faculty of Medicine, Sohag University, Sohag, Egypt
  • Mohammad A. Abusedera Department of Radiology, Sohag University Hospital, Faculty of Medicine, Sohag University, Sohag, Egypt
  • Hitham M. Ali Departemnt of Anesthesia and Intensive Care, Sohag University Hospital, Faculty of Medicine, Sohag University, Sohag, Egypt

DOI:

https://doi.org/10.18203/2349-2902.isj20164052

Keywords:

Pancreatico-gastrostomy, Pancreatictomy, Whipple

Abstract

Background:Pancreatico-gastrostomy (PG) is widely applied for restoration of connection between the distal pancreatic remnant and digestive tract during Whipple procedure. Comparative studies on the clinical outcome of various PG techniques are scarce.

Methods: Medical records of patients who underwent PG at Sohag University Hospital (November 2012-December 2015) were reviewed. Patients who had PG using our new technique of enveloped double purse-string sutures (EDPS-PG) were compared with control group of conventional transfixing suture PG regarding the postoperative outcome.

Results:Twenty-seven patients (18 conventional PG and 9 EDPS-PG) were enrolled. Grade C postoperative pancreatic fistula (POPF) occurred only in the conventional PG group. Patients in the EDPS-PG group needed significantly shorter time before removal of the abdominal drains (p = 0.04), significantly reduced length of hospital stay (p = 0.03) and significantly lower grades of postoperative complications (p = 0.02) compared with the conventional PG group. Postoperative death occurred only in one patient in the control group. No significant difference could be found regarding operative time, postoperative bleeding delayed gastric emptying or bile leak.

Conclusions:EDPS-PG is new, simple and safe technique for PG during Whipple procedure and results in significant reduction of POPF and overall complications.

Metrics

Metrics Loading ...

References

Guerrini GP, Soliani P, D'Amico G, Di Benedetto F, Negri M, Piccoli M, et al. Pancreatico jejunostomy versus pancreatico gastrostomy after pancreatico duodenectomy: an up-to-date meta-analysis. J Invest Surg. 2016;29(3):175-84.

Takahashi S, Gotohda N, Kato Y, Konishi M. Measure of pancreas transection and postoperative pancreatic fistula. J Surg Res. 2016;202:276-83.

Qin H, Luo L, Zhu Z, Huang J. Pancreatic gastrostomy has advantages over pancreaticojejunostomy on pancreatic fistula after pancreaticoduodenectomy. A meta-analysis of randomized controlled trials. Int J Surg Lond Engl. 2016;36:18-24.

Aranha GV. Pancreaticogastrostomy. Oper Tech. Gen Surg. 2001;3:54-60.

Zenilman ME. Use of pancreatic gastrostomy for pancreatic reconstruction after pancreatico duodenectomy. J Clin Gastroenterol. 2000;31:11-8.

Telford GL, Mason GR. Pancreatico gastrostomy: clinical experience with a direct pancreatic duct to gastric mucosa anastomosis. Am J Surg. 1984;147:832-7.

Shinchi H, Takao S, Maemura K, Aikou T. A new technique for pancreatic gastrostomy for the soft pancreas: the transfixing suture method. J Hepatobiliary Pancreat Surg. 2006;13:212-7.

Peng SY, Wang JW, Hong DF, Liu YB, Wang YF. Binding pancreaticoenteric anastomosis: from binding pancreatico jejunostomy to binding pancreatico gastrostomy. Updat Surg. 2011;63:69-74.

Feng QY, Wei Y, Chen JW, Chang WJ, Ye LC, Zhu DX, et al. Anti-EGFR and anti-VEGF agents: important targeted therapies of colorectal liver metastases. World J Gastroenterol. 2014;20:4263-75.

Addeo P, Rosso E, Fuchshuber P, Oussoultzoglou E, Souche R, Nobili C, et al. Double purse-string telescoped pancreatic gastrostomy: an expedient, safe, and easy technique. J Am Coll Surg. 2013;216: e27-33.

Narita M, Matsusue R, Hata H, Yamaguchi T, Otani T, Ikai I. Double purse-string telescoped pancreatic gastro stomy using an atraumatic self-retaining ring retractor in a subtotal stomach-preserving pancreatico duodenectomy. Ann Surg Oncol. 2016;23:1034.

Wang XA, Wu XS, Cai Y, Jin HC, Shen WM, Liu YB, et al. Single purse-string duct to mucosa pancreatic gastrostomy: a safe, easy, and useful technique after pancreatico duodenectomy. J Am Coll Surg. 2015;220:e41-48.

Yeo CJ, Cameron MM, Maher PK, Sauter ML Zahurak MA, Talamini KD, et al. A prospective randomized trial of pancreatic gastrostomy versus pancreatico jejunostomy after pancreatico duodenectomy. Ann Surg. 1995;222: 580-588.

Duffas JP, Suc B, Msika S, Fourtanier G, Muscari F, Hay JM, et al. A controlled randomized multicenter trial of pancreato gastrostomy or pancreato jejunostomy after pancreato duodenectomy. Am J Surg. 2005;189; 720-9.

Fernández-Cruz L, Belli A, Acosta M, Chavarria EJ, Adelsdorfer W, López-Boado MA, et al. Which is the best technique for pancreaticoenteric reconstruction after pancreatico duodenectomy? A critical analysis. Surg Today. 2011;41:761-6.

Chen, Z. Pancreaticogastrostomy versus pancreatico jejunostomy after pancreaticoduodenectomy: a meta-analysis of randomized control trials. Br Assoc Surg Oncol. 2014;40:1177-85.

Figueras J, Sabater L, Planellas P, Muñoz-Forner E, Lopez-Ben S, Falgueras L, et al. Randomized clinical trial of pancreatico gastrostomy versus pancreatico jejunostomy on the rate and severity of pancreatic fistula after pancreaticoduodenectomy. Br J Surg. 2013;100:1597-605.

Lei P, Fang J, Huang Y, Zheng Z, Wei B, Wei H. Pancreatico gastrostomy or pancreatico jejunostomy? Methods of digestive continuity reconstruction after pancreatico dudenectomy: a meta-analysis of randomized controlled trials. Int J Surg Lond Engl. 2014;12:1444-9.

Ma S, Li Q, Dai W, Pan F. Pancreatico gastrostomy versus pancreatico jejunostomy. J Surg Res. 2014;192:68-75.

Xiong JJ, Tan CL, Szatmary P, Huang W, Ke NW, Hu WM, et al. Meta-analysis of pancreatic gastrostomy versus pancreatico jejunostomy after pancreatico duodenectomy. Br J Surg. 2014;101:1196-208.

Hallet J, Zih FS, Deobald RG, Scheer AS, Law CH, Coburn NG, et al. The impact of pancreatico jejunostomy versus pancreatico gastrostomy reconstruction on pancreatic fistula after pancreatico duodenectomy: meta-analysis of randomized controlled trials. HPB. 2015;17:113-22.

Menahem B, Guittet L, Mulliri A, Alves A, Lubrano J. Pancreatico gastrostomy is superior to pancreatico jejunostomy for prevention of pancreatic fistula after pancreatico duodenectomy: an updated meta-analysis of randomized controlled trials. Ann Surg. 2015;261:882-7.

Que W, Fang H, Yan B, Li J, Guo W, Zhai W, et al. pancreatic gastrostomy versus pancreatico jejunostomy after pancreatico duodenectomy: a meta-analysis of randomized controlled trials. Am J Surg. 2015;209:1074-82.

Katz MHG, Ahmad SA, Boughey JC. Improving resection rates in borderline resectable pancreatic cancer: Pilot study shows favorable results. Bull Am Coll Surg. 2015;100:39-41.

Pisters PWT. Standard pancreato duodenectomy. Oper Tech Gen Surg. 2001;3:17-30.

Farnell MB. Pylorus - preserving pancreato duodenectomy. Oper Tech Gen Surg. 2001;3:31-44.

Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J, et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery. 2005;138:8-13.

Wente MN, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the international study group of pancreatic surgery (ISGPS). Surgery. 2007;142: 761-8.

Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187-96.

Delcore R, Thomas JH, Pierce GE, Hermreck AS. Pancreato gastrostomy: a safe drainage procedure after pancreatoduodenectomy. Surgery. 1990;108:641-7.

Downloads

Published

2016-12-13

How to Cite

El-Badry, A. M., Redwan, A. A., Abusedera, M. A., & Ali, H. M. (2016). Enveloped double purse-string versus conventional pancreatico-gastrostomy during Whipple procedure: comparative study at Sohag university onco-surgery program. International Surgery Journal, 4(1), 58–63. https://doi.org/10.18203/2349-2902.isj20164052

Issue

Section

Original Research Articles