Comparison between two mixtures of lidocaine and bupivacaine for infraclavicular block: a double blind randomized trial

Authors

  • El Kaissi Jaber Anesthesiology and Intensive Care Department, Moulay Ismail Military Hospital, Meknes, Morocco; Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco http://orcid.org/0000-0003-1696-4819
  • El Moqaddem Amine Department of Emergency, Moulay Ismail Military Hospital, Meknes, Morocco; Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco
  • Khalil Mounir Anesthesiology and Intensive Care Department, Moulay Ismail Military Hospital, Meknes, Morocco; Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco
  • Kechna Hicham Anesthesiology and Intensive Care Department, Moulay Ismail Military Hospital, Meknes, Morocco; Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco
  • Hachimi Moulay Ahmed Anesthesiology and Intensive Care Department, Moulay Ismail Military Hospital, Meknes, Morocco; Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco
  • Laoutid Jaouad Faculty of Medicine, Sidi Mohamed Ben Abdellah University, Fes, Morocco

DOI:

https://doi.org/10.18203/2349-2902.isj20201844

Keywords:

Analgesia, Local anaesthetics, Nerve block

Abstract

Background: We compare the two mixtures in terms of efficiency, analgesia, and side effects.

Methods: 30 patients scheduled for upper limb surgery were randomized in 2 groups. the group A received a mixture of 50% lidocaine 2% and 50% of bupivacaine 0.5% the group B received a mixture of 75% lidocaine 1% and 25% of bupivacaine 0.5%. Volumes, block onset times, blocks duration times, analgesia, and toxicity were compared.

Results: The volumes were equals in both groups. Sensory block onset was 5.43 min in the group A versus 6.73 min in the group B, motor block onset was 11.93 for the group A versus 13.46 min for the group B. Sensory block duration was 5.48 hours in the group A versus 4.05 hours for the group B (p=0.037), motor block duration was 7.75 hours for group A versus 5.50 hours for group B (p=0.014). Analgesia levels are equals between the two groups, there was no side effects listed.

Conclusions: The use of low concentrated lidocaine and bupivacaine mixture induces an adequate anaesthesia and decreases the duration of motor block with a reduced level of pain and an equal level of analgesia.

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Published

2020-04-23

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Original Research Articles