Clinicopathological evaluation of thyroid incidentaloma: a prospective study

Authors

  • P. B. Thrishuli Department of Surgery, JSS Medical College, Mysuru, Karnataka, India
  • N. Mallikarjunarao Medam Department of Surgery, JSS Medical College, Mysuru, Karnataka, India

DOI:

https://doi.org/10.18203/2349-2902.isj20163996

Keywords:

Fine needle aspiration biopsy, Incidental thyroid nodule, Thyroid cancer, Ultrasound

Abstract

Background:Incidental thyroid nodules are typically non-palpable thyroid nodules found during radiographic evaluation for a non-thyroid related issue (USG neck, CT scan, PET scan, carotid duplex).The prevalence of thyroid incidentalomas ranges from 1.6% to 67% based on radiographic modality of detection. The rate of malignancy in incidental thyroid nodule can again quite variable based on how it was discovered and range from 4% to 50%. (The overall risk is approximately 15%).

Methods: A prospective study was carried out in 100 patients. Discovery of a thyroid nodule by imaging investigations in individuals, who are asymptomatic for thyroid disease, was done in the study. FNAC of the nodule is done to know the pathology.

Results:Incidence of thyroid incidentaloma was found to be 9%. In 40 patients who underwent carotid doppler the incidence was found to be 10%. In 50 patients who underwent USG neck, the incidence was found to be 10%. There was no incidentaloma detected in CT done in the 10 patients observed in this study. 9 patients with thyroid incidentalomas out of which 7 patients diagnosed benign lesion and 2 patients diagnosed with malignancy.

Conclusions:Incidence of thyroid incidentaloma in our study is comparable to worldwide statistics. The incidence of incidentaloma (9%) and malignant pathology (22.2%) picked up in incidentalomas in our study is going in favour of advocating screening programme in our population (>50 years). USG neck appears to be most suitable investigation for screening.

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References

Ezzat S, Sarti DA, Cain DR. Thyroid incidentalomas prevalence by palpation and ultrasonography. Archives Internal Med. 1994;154(16):1838-40.

Youserm DM, Huang T, Loevner LA. Clinical and economic impact of incidental thyroid lesions found with CT and MR. Am J Neuroradiol. 1997;18(8):1423-8.

Steele SR, Martin MJ, Mullenix PS. The significance of incidental thyroid abnormalities identified during carotid duplex ultrasonography. Archives Surg. 2005;140(10):981-5.

Cohen MS, Arslan N, Dehdashti F. Risk of malignancy in thyroid incidentalomas identified by fluorodeoxyglucosepositron emission tomography. Surgery. 2001;130(6):941-6.

Liebeskind A, Sikore AG, Komisar A. Rates of malignancy in incidentally discovered thyroid nodules evaluated with sonography and fine needle aspiration. J Ultrasound Med. 2005;24:629-34.

Shetty SK, Maher MM, Hahn PF. Significance of incidental thyroid lesion detected on CT: correlation among CT, sonography and pathology. AJR Am J Roentgenol. 2006;187:1349-56.

Kim TY, Kim WB, Ryu JS, et al. 18F-flourodeoxyglucose uptake in thyroid from PET for evaluation of cancers patients: high prevalence of malignancy in thyroid PET incidentaloma. Laryngoscope. 2005;115:1074-8.

Jin J, Wilhelm SM, Mchenry CR. Incidental thyroid nodule: patterns of diagnosis and rate of malignancy. Am J Surg. 2009;197:320-4.

Wiest PW, Hartshorne MF, Inskip PD, Crooks LA, Vela Bs, Telepak RJ, et al. Thyroid palpation versus highresolution thyroid ultrasonography in the detection of nodules. J Ultrasound Med. 1998;17:487-96.

Brander A, Viikinkowski P, Nickels J. Thyroid gland: US screening in a random adult population. Radiology. 1991;181:683-7.

Dean DS, Gharib H. Epidemiology of thyroid nodules. Clin Endocrinol Metab. 2008;22:901-11.

Mohammadi A, Amirazodi E, Masudi S, Pedram A. Ultrasonographic prevalence of thyroid incidentaloma in Bushehr, south Iran. Iran J Radiol. 2009;6:65-8.

Caroll BA. Asymptomatic thyroid nodules: incidental sonographic detection. Am J Roentgenol. 1982;138:499-501.

Kang HW, No JH, Chung JH, Min YK, Lee MS, Lee MK, et al. Prevalence, clinical and ultrasonographic characteristics of thyroid incidentalomas. Thyroid. 2004;14:29-33.

Karaszewski B, Wilkowski M, Tomasiuk T, Szramkowska M, Klaska A, Obolonczyk L, et al. The prevalence of incidentaloma asymptomatic thyroid nodule in Tricity (Gdansk, Sopot, Gdynia) population. Endokrynol Pol. 2006;57:196-200.

Taheri MS, Hemadi H, Haghighatkhah HR, Kamyar K, Jalali AH, Shakiba M. Prevalence of incidental thyoid nodules diagnosed by ultrasound in an Iranian population. Iran J Radiol. 2008;5:19-23.

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Published

2016-12-13

How to Cite

Thrishuli, P. B., & Mallikarjunarao Medam, N. (2016). Clinicopathological evaluation of thyroid incidentaloma: a prospective study. International Surgery Journal, 4(1), 39–42. https://doi.org/10.18203/2349-2902.isj20163996

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Original Research Articles