Incidence and management of intestinal perforation in typhoid: a prospective, observational study
DOI:
https://doi.org/10.18203/2349-2902.isj20201871Keywords:
Enteric fever, Enteric perforation, Intestinal perforation, TyphoidAbstract
Background: Intestinal perforation is a common surgical problem, which need proper attention. Typhoid is the most common cause of bowel perforation. With the concept of a correct diagnosis of perforation in reference to its etiology and further study of etiological factor (typhoid) in relation to epidemiology, surgical treatment and outcome, the present study has been undertaken.
Methods: It is a prospective, observational study in which 50 cases of enteric perforation admitting in SMS Hospital at JAIPUR were observed. All patients of enteric perforation peritonitis were evaluated by detailed history, clinical examination and radiological as well as laboratory investigations. After initial resuscitation patient were treated by operative procedures. Postoperatively progress report, morbidity and mortality data were observed.
Results: Mean age of patients was 26.38 years. Male to female ratio was 4:1. Enteric perforation is more common in patients with poor nutritional status and rural area. Primary repair of perforation was done in patient with small perforation with relatively healthy bowel, while ileostomy was done in patients with large perforation of longer duration, multiple perforations and edematous bowel with necrotic patches. Mortality was highest in patients who underwent primary repair and proximal loop ileostomy (33.3%) and lowest in patients in which exteriorization of the perforation as loop ileostomy was done (10.3%).
Conclusions: The time interval between occurrence of perforation and starting of specific therapy is the most important factor in deciding the ultimate outcome of the typhoid perforation patient and operative procedure is another important factor in deciding the outcome.
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References
Nair SK, Singhal VS. Non-traumatic intestinal perforation. Indian J Surg. 1981;43(5):371-7.
Mishra SB, Prusty PN, Mishra BP. Surgical treatment of acute perforated duodenal ulcer. US. 1982;5:705-9.
Dickson JAS, Cole GJ. Perforation of terminal ileum, a review of 38 cases. BJS. 1964;51:893-7.
Matsukara Y. Clinical research on patients with typhoid and paratyphoid fever. Japan Assoc Inf Dis. 1991;65(6):710-7.
Park K. Preventive & Social Medicine, 23rd Edition, Kuppuswamy's Socioeconomic Status Scale; 2015: 690.
Park K. Preventive & social medicine. 16th Edition; Banarsidas Bhanot Publishers, India; 2000: 176.
Vyas PN. A study of 15 cases of intestinal perforation in enteric fever. Indian J Surg. 1964;26:1-8.
Vaidyanathan S. Surgical management of typhoid ileal perforation. Indian J Surg. 1986;48:335-41.
Archampong EQ. Operative treatment of typhoid perforation of bowel. Br Med J. 1969;3:273-6.
Franklin WPL. Study of typhoid perforation. BJS. 1963;50:976-9.
Shah JS. Enteric perforation: a review of 40 cases. J Physcian In. 1967;15:537-41.
Purohit PG. Surgical treatment of typhoid perforation. Indian J Surg. 1978;40:227-38.
Chauhan MK, Pande SK. A review of 344 patients with typhoid perforation. BJS. 1982;69:173-5.
Huckstep RL. Recent advances of typhoid fever. Ann R Coll Surg Engl. 1960;26:207-23.
Kaul BK. Operative management of typhoid perforation in children. Int Surg. 1975;60:407-10.
Lizarralde AE. Typhoid perforation of ileum in children. J Pead Surg. 1981;16:1012-6.
Eggleston FC, Santoshi B, Singh CM. Typhoid perforation of the bowel experience in 78 cases. Ann Surg. 1979;190(1):31-5.
Karmarkar SR, Trivedi B, Bhalarao RA. Perforation of terminal ileum. Indian J Surg. 1972;34:422-6.
Vergas M, Pena A. Perforated viscera in typhoid fever. J Pediatr Surg. 1975;10(4):531-2.
Rathore AH. Prognostic indices of typhoid perforation. Ann Trop Med Parasitology. 1987;81(3):278.