DOI: http://dx.doi.org/10.18203/2349-2902.isj20200849

Mucormycosis presenting as gastric perforation peritonitis in a malnourished young adult: a rare case report

Dheer Singh Kalwaniya, Vignesh Mani, Ravi Shekhar Pradhan, Jaspreet Singh Bajwa, Monish Raj

Abstract


Mucormycosis is a rare infection which is largely diagnosed in immune-compromised patients. The infection can cause pulmonary, rhinocerebral, skin and soft tissue, central nervous system, gastrointestinal and disseminated disease, with gastrointestinal involvement being the rarest presentation. Outcome and mortality of zygomycosis varies with the underlying condition and site of infection, it is however very high in general. Diagnosis is usually delayed and delay in initiation of amphotericin B treatment leads to poor outcome. We report rare case of a malnourished young adult who presented with gastric perforation peritonitis due to mucormycosis infection.


Keywords


Gastric perforation, Gastrointestinal, Mucormycosis

Full Text:

PDF

References


Velázquez VP, Pera M, Gimeno J, Zapatero A, Nolla J, Pera M. Mucormycosis: an unusual cause of gastric perforation and severe bleeding in immunocompetent patients. Rev Esp Enferm Dig. 2017;109(3):223-5.

Jung JH, Choi HJ, Yoo J, Kang SJ, Lee KY. Emphysematous gastritis associated with invasive gastric mucormycosis: a case report. J Korean Med Sci. 2007;22(5):923-7.

Kulkarni RV, Thakur SS. Invasive gastric mucormycosis-a case report. Indian J Surg. 2015;77(1):87-9.

Kontoyiannis DP, Lewis RE. Invasive zygomycosis: update on pathogenesis, clinical manifestations, and management. Infect Dis Clin North Am. 2006;20:581-607.

Prasad SBN, Shenoy A, Nataraj KS. Primary gastrointestinal mucormycosis in an immunocompetent person. J Postgrad Med. 2008;54:211-3.

Spellberg B. Gastrointestinal mucormycosis: an evolving disease. Gastroenterol Hepatol (NY). 2012;8:140-2.

Petrikkos G, Skiada A, Sambatakou H, Toskas A, Vaiopoulos G, Giannopoulou M, Katsilambros N. Mucormycosis: ten-year experience at a tertiary-care center in Greece. Eur J Clin Microbiol Infect Dis. 2003;22(12):753-6.

Rickerts V, Atta J, Herrmann S. Successful treatment of disseminated mucormycosis with a combination of liposomal amphotericin B and posaconazole in a patient with acute myeloid leukemia. Mycoses. 2006;49(1):27-30.

Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, Sein M, Sein T, Chiou CC, Chu JH, Kontoyiannis DP. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005;41:634-53.

Alvarado-Lezama J, Espinosa-González O, García-Cano E, Sánchez-Córdova G. Emphysematous gastritis secondary to gastric mucormycosis. Cir Cir. 2015;83(1):56-60.

Song KY, Kang WK, Park CW, Choi YJ, Rha SE, Park CH. Mucormycosis resulting in gastric perforation in a patient with acute myelogenous leukemia. Surg Today. 2006;36:831-4.