Role of nano-collagen particles dressing in the management of chronic ulcer: a prospective non-randomized trial on 100 cases


  • Mahinder Pal Kochar Department of General Surgery, Jaipur National University Institute of Medical Sciences and Research Center, Jaipur, Rajasthan, India
  • Satyendra Pal Singh Department of General Surgery, NIMS Medical College and Hospital, Jaipur, Rajasthan, India



Chronic ulcer, Dressing, Nano collagen particles


Background: Collagen has unique property of adhere to the ulcer floor thus reduces plasma oozing, bacterial colonization, pain and ulcer size which boost the process of granulation and epithelialization thus healing.

Methods: In this prospective, non-randomized study 100 patients of different age and sex having chronic ulcer situated on various parts of the body were taken. Nano collagen particles preparation “collofibre” of TNC health care was used.

Results: Most of the patients fall in their most productive life (3rd and 4th decade), restricted mobility due to pain. Thus anaemia, diabetes, old age, debility, bed ridden situations, other associated injuries and certain medical conditions contribute to delay in ulcer healing and hospital stay. Bacterial contamination, presence of necrotic tissue and slough delay the healing process. 73% of patients complain of itching and burning sensation after application otherwise no major side effect detected.

Conclusions: Use of nano collagen particles dressing accelerate the healing process in chronic ulcers.


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